Yearbook of Intensive Care and Emergency Medicine pp 866-874 | Cite as
Treatment of Post-Traumatic Brain Edema
Abstract
Brain edema with raised intracranial pressure (ICP) often constitutes a serious complication of traumatic head injury and may be fatal. High ICP may compromise perfusion to the brain and cause tentorial herniation and brain stem compression, the latter in fact being the most important cause of death in this category of patients. The overall mortality/morbidity for deeply comatose patients with severe head injuries and raised ICP is high and is often reported to exceed 50% [1–4]. High ICP and low cerebral perfusion pressure (CPP) are prognostic factors discussed as correlating to poor outcome [1–3, 5]. Impaired vasoreactivity to hyperventilation in combination with raised ICP is the factor shown to correlate best to poor outcome with a mortality/vegetativity/severe disability rate of close to 100% [6].
Keywords
Cerebral Perfusion Pressure Severe Head Injury Colloid Osmotic Pressure Tissue Pressure Albumin InfusionPreview
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