Abstract
While the histopathologist has relatively little difficulty in making the diagnosis of prostatic adenocarcinoma, the clinician may have considerable problems in deciding what this diagnosis implies for the patient. A proportion of adenocarcinomas do not seem to progress and are thus “latent”. This has been demonstrated from step-sectioning of prostates examined after autopsy which shows that, irrespective of the incidence of invasive prostatic cancer in the population of origin, the frequency of small “latent” cancers does not appear to vary much across populations (Breslow et al. 1977). This implies that varying proportions of these tumours do not progress to the clinically manifest form. Any series of prostate cancer contains a proportion of tumours which do not behave in a truly malignant fashion.
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Gould, A., Muir, C.S., Sharp, L. (1995). Prognosis and Survival in Prostate Cancer. In: Garraway, M. (eds) Epidemiology of Prostate Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78826-0_20
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DOI: https://doi.org/10.1007/978-3-642-78826-0_20
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