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Analysis of the Short Tandem Repeat Polymorphism TC 11 (HUMTH01): Allele Frequencies and Family Studies

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Advances in Forensic Haemogenetics

Part of the book series: Advances in Forensic Haemogenetics ((HAEMOGENETICS,volume 5))

Abstract

Short tandem repeat (STR) polymorphisms provide a potential tool to forensic casework. In order to use the system TC 11 (HUMTH01: human tyrosine hydroxylase intron 1 on chromosome 11 (1)) in forensic DNA analysis, detailed knowledge of allele frequencies is most important. In paternity cases it is also essential to know the mutation rate. For this reason we analysed unrelated individuals and families from Northern Germany.

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Literature

  1. Edwards, A., Civitello, A., Hammond, H.A., Caskey, T. 1991. DNA typing and genetic mapping with trimeric and tetrameric tandem repeats. Am. J. Hum. Genet. 49: 746–756.

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  2. Edwards, A., Hammond, H.A., Jin, L., Caskey, T., Chakraborty, R. 1992. Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups. Genomics 12: 241–253.

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Author information

Authors and Affiliations

  1. Inst. für Blutgruppenforschung, Otto-Hahn-Str. 39, P.O. Box 13 04 68, D-40554, Duesseldorf, Germany

    P. Berschick, L. Henke & J. Henke

Authors
  1. P. Berschick
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  2. L. Henke
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  3. J. Henke
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Editor information

Editors and Affiliations

  1. Institut für Rechtsmedizin, Universität Zürich-Irchel, Winterthurerstrasse 190, CH-8057, Zürich, Switzerland

    Walter Bär

  2. Istituto di Medicina Legale, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, I-00168, Roma, Italy

    Angelo Fiori

  3. Servizio Ematologia e Centro Trasfusionale, Ospedale Civile Legnano, I-20025, Legnano (Milano), Italy

    Umberto Rossi

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© 1994 Springer-Verlag Berlin Heidelberg

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Berschick, P., Henke, L., Henke, J. (1994). Analysis of the Short Tandem Repeat Polymorphism TC 11 (HUMTH01): Allele Frequencies and Family Studies. In: Bär, W., Fiori, A., Rossi, U. (eds) Advances in Forensic Haemogenetics. Advances in Forensic Haemogenetics, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78782-9_127

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  • DOI: https://doi.org/10.1007/978-3-642-78782-9_127

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-57643-3

  • Online ISBN: 978-3-642-78782-9

  • eBook Packages: Springer Book Archive

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