The Parasitophorous Vacuole Membrane Surrounding T. Gondii: A Specialized Interface Between Parasite and Cell

  • Keith A. Joiner
Conference paper
Part of the NATO ASI Series book series (volume 78)

Abstract

Cell invasion by apicomplexan parasites is a rapid yet highly ordered process dependent upon oriented attachment of the parasite to the target cell, parasite motility, and secretion of anterior organelles (rhoptries) during the invasion event (reviewed in Werk 1985). Subsequent to invasion of the host cell, the apicomplexan parasite, Toxoplasma gondii, resides within a specialized parasitophorous vacuole (PV). Unlike phagolysosomes, the parasitophorous vacuole neither fuses with lysosomes nor acidifies [Joiner et al. 1990; Jones and Hirsch 1972; Sibley et al. 1985].

Keywords

Toxoplasma Gondii Nucleoside Transport Parasitophorous Vacuole Apicomplexan Parasite Putative Transmembrane Domain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • Keith A. Joiner
    • 1
  1. 1.Section of Infectious Diseases Department of MedicineYale University School of MedicineNew HavenUSA

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