Intensivtherapie bei schwerer Pankreatitis

  • E. Martin
  • H. Schmidt
Conference paper
Part of the Refresher Course — Aktuelles Wissen für Anästhesisten book series (REFRESHER COUR, volume 19)

Zusammenfassung

Die akute Pankreatitis stellt ein Krankheitsbild mit einem breiten Spektrum klinischer Erscheinungsformen dar. Schätzungsweise 80% der akuten Episoden zeigen einen milden, selbstlimitierenden Verlauf. Das pathomorphologische Bild ist hierbei durch ein interstitielles Ödem des Pankreas mit minimalen Fettgewebsnekrosen gekennzeichnet. Diese Patienten zeigen unter einer supportiven Basistherapie ohne spezifische Behandlungsverfahren eine raschen Rückgang der klinischen Symptomatik [1]. Die bei 5–20% aller Pankreatitiden auftretende schwere, nekrotisierende Verlaufsform ist aufgrund der assoziierten renalen, pulmonalen und hämodynamischen Komplikationen durch eine hohe Letalität gekennzeichnet [2]. Morbidität und Letalität der nekrotisierenden Pankreatitis werden von der Wirkung vasoaktiver und toxischer Substanzen, der Ausdehnung von Fettgewebs- und Parenchymnekrosen sowie einer sekundären bakteriellen Kolonisation des nekrotischen Materials bestimmt [3].

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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • E. Martin
  • H. Schmidt

There are no affiliations available

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