Recent Advances in the Chemistry of Quinolones

  • Daniel Bouzard
Chapter

Abstract

Nalidixic acid was first introduced in therapy in 1963, about 15 years later a new generation of quinolones with broader spectrum of activity appeared: the fluoroquinolones; since then about 6000 new analogs have been disclosed and about 20 derivatives are marketed or in advanced development.

Keywords

Nalidixic Acid Fluorine Atom Oxolinic Acid Pipemidic Acid Nucleophilic Displacement 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • Daniel Bouzard
    • 1
  1. 1.Bristol-Myers Squibb FranceResearch LaboratoriesMarne la Vallee Cedex 2France

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