Automated Cytogenetics in the Study of Mutagenesis and Cancer

  • J. Piper
Part of the Advances in Mutagenesis Research book series (MUTAGENESIS, volume 2)

Abstract

After almost three decades of research and development, cytogenetics automation now provides practical and cost effective assistance in some subject areas, notably in clinical cytogenetics for the determination of the human constitutional karyotype, for example for ante-natal screening of genetic disorders (Piper and Lunds-teen 1987; Lundsteen and Martin 1989; Rutovitz 1989). While much of the knowledge and technology is relevant to aspects of mutagenesis, it was with few exceptions not developed with these studies in mind.

Keywords

Image Region Medial Axis Sister Chromatid Exchange Dicentric Chromosome Chromosome Cluster 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • J. Piper
    • 1
  1. 1.MRC Human Genetics UnitWestern General HospitalEdinburghScotland, UK

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