Abstract
The combination of temperature and various intravascular indicators [4, 6, 9, 10, 11, 13] has been used since 1966 [12] to determine extravascular lung thermal volume, which is a measure of “true” pulmonary extravascular water. Probably the best estimates of pulmonary extravascular water are available from gravimetric techniques and range from 4 to 5 ml/kg [13, 14]. In contrast, extravascular lung thermal volume, as reported from different laboratories, is in the order of 6–10 ml/kg [4, 6, 9, 10, 11, 12, 13]. The possibility that the thermal indicator equilibrates with extrapulmonary structures like right and left myocardium has been discussed in the literature [6, 9, 11, 14, 15]. The adequacy of monoexponential extrapolation to clear the dilution curves from the effects of indicator recirculation has so far been assumed but not verified.
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Böck, J., Hoeft, A., Korb, H., Steinmann, J., Wolpers, HG., Hellige, G. (1990). A Comparison of Extrapolation and Deconvolution of Thermo-Dye Dilution Curve, with Special Emphasis on States with Early Indicator Recirculation. In: Lewis, F.R., Pfeiffer, U.J. (eds) Practical Applications of Fiberoptics in Critical Care Monitoring. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75086-1_12
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DOI: https://doi.org/10.1007/978-3-642-75086-1_12
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