Summary
Senile macular degeneration is a frequent cause of blindness for which there is no satisfactory medical treatment. A double-blind trial comparing Ginkgo biloba extract with a placebo was conducted in 10 out-patients at the Hôtel Foch. Drug effectiveness was assessed on the results of fundoscopy and of measurements of visual acuity and visual field.
In spite of the small population sample, a statistically significant improvement in long distance visual acuity was observed after treatment with Ginkgo biloba extract. The assumed pathogenesis of senile macular degeneration is discussed with emphasis on free oxygenated radicals.
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References
Coscas G.: Pathogénie de la dégénérescence maculaire sénile. Bull. Soc. Belge Ophtal., 1984, 209, 117–127.
Doly M., Braquet P.: Effet des radicaux libres oxygénés sur l’activité électrophysiologique de la rétine isolée de rat. J. Fr. Ophtalmol., 1985, 8, 273–277.
Gass J.D.M.: Pathogenesis of disciform detachment of the neuro-epithelium. Am. J. Ophtalmol., 1967, 63, 573.
Kornzweig A.L.: Changes in the choriocapillaris associated with senile macular degeneration. Annal. Ophtalmol., 1977, 9, 753–764.
Ryan S.7.: Subretinal neo-vascularization after argon laser photocoagulation. Arch. KIM Ophtalmol., 1980, 215, 29–42.
Sarks S.H.: Drusen and their relationship to senile macular degeneration. Austral. J. Ophtalmol., 1980, 8, 117–130.
Toczynski E., Tso M.O.M.: The architecture of the choriocapillaris at the posterior pole. Am. J. Ophtalmol., 1976, 81, 428–440.
Tso M.: Pathogenic factors of aging macular degeneration. Ophtalmology.,1985, 92,628–635
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© 1988 Springer-Verlag Berlin Heidelberg New York
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Lebuisson, D.A., Leroy, L., Rigal, G. (1988). Treatment of Senile Macular Degeneration with Ginkgo Biloba Extract. In: Fünfgeld, E.W. (eds) Rökan. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73686-5_25
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DOI: https://doi.org/10.1007/978-3-642-73686-5_25
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-19261-9
Online ISBN: 978-3-642-73686-5
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