Systemic Lupus Erythematosus pp 345-354 | Cite as
Future Immunotherapeutic Possibilities in Autoimmunity
Abstract
Autoimmune diseases are multifactorial and involve genetic, viral, hormonal, environmental, and emotional components. Any or all of these factors can contribute to a breakdown in normal immunologic control which is at the heart of the autoimmune problem. The chronic autoimmune and inflammatory diseases are fundamentally disorders of immunologic regulation in which the immune system makes mistakes and unleashes a series of inappropriate effector mechanisms resulting in target organ destruction. The target organ may be synovial tissue lining joint surfaces (as in rheumatoid arthritis), the brain (as in multiple sclerosis), or almost any organ in the body.
Keywords
Systemic Lupus Erythematosus Major Histocompatibility Complex Lupus Nephritis Myelin Basic Protein Autoimmune ThyroiditisPreview
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References
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