Future Immunotherapeutic Possibilities in Autoimmunity

  • N. Talal

Abstract

Autoimmune diseases are multifactorial and involve genetic, viral, hormonal, environmental, and emotional components. Any or all of these factors can contribute to a breakdown in normal immunologic control which is at the heart of the autoimmune problem. The chronic autoimmune and inflammatory diseases are fundamentally disorders of immunologic regulation in which the immune system makes mistakes and unleashes a series of inappropriate effector mechanisms resulting in target organ destruction. The target organ may be synovial tissue lining joint surfaces (as in rheumatoid arthritis), the brain (as in multiple sclerosis), or almost any organ in the body.

Keywords

Systemic Lupus Erythematosus Major Histocompatibility Complex Lupus Nephritis Myelin Basic Protein Autoimmune Thyroiditis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 1987

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  • N. Talal

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