Effects of 13 Mutagens on Rat Hepatic Microsomal Enzymes

  • Liu Yu-Gu
Chapter

Abstract

Hepatic microsomal enzymes are the important enzymes involved in the biotransformation of carcinogens. It is known that many drugs, insecticides, and toxic metals are inhibitors of microsomal enzymes and that they can influence the microsomal metabolism of various drugs, mutagens, carcinogens, and other toxic compounds in the body. The purpose of the present study was to examine the effect of cadmium, mercury, lead, arsenic, chromium, DDT, chlordimeform, trichlorfon, benzo(a)pyrene, aflatoxin B1, dimethylnitrosamine, cyclophosphamide, and mitomycin C on the activities of hepatic microsomal enzymes in rats.

Keywords

Microsomal Enzyme Propyl Gallate Mixed Function Oxidase Treatment Cadmium Hepatic Microsomal Enzyme 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag 1987

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  • Liu Yu-Gu

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