Osmotic Control of Aldosterone Secretion
Abstract
Aldosterone, a mineralocorticoid hormone synthesized from cholesterol by a series of enzymatic reactions within the glomerulosa cells of the adrenal cortex, is involved in the maintenance of both sodium and potassium balance. Aldosterone acts on a variety of tissues, such as distal nephrons, salivary glands, sweat glands, and parts of the intestinal tract to alter sodium and potassium transport. We will make no attempt to detail the processes involved in how aldosterone effects sodium and potassium transport since several of the accompanying papers address this important and interesting issue. However, the consequences of the action of aldosterone are to stimulate sodium conservation and to increase the rate at which potassium is excreted from the body. Being able to regulate the concentration of aldosterone in the blood is critical for the regulation of both sodium and potassium balance.
Keywords
Plasma Renin Activity Sodium Concentration Water Deprivation Extracellular Compartment Aldosterone SecretionPreview
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References
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