Mononitrates pp 201-214 | Cite as
Beneficial Effects of Isosorbide-5-Mononitrate on Exercise Performance in Patients with Chronic Stable Angina Pectoris
Conference paper
Abstract
IS-5-MN, an active metabolite of isosorbide dinitrate (ISDN), has been used as a pharmacological compound in patients with stable angina pectoris during their usual activities or when submitted to stress tests, with excellent clinical results [1,2].
Keywords
Exercise Test Angina Pectoris Peak Exercise Chronic Stable Angina Isosorbid Dinitrat
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Preview
Unable to display preview. Download preview PDF.
References
- 1.Müller G, Schmidt Voigt J (1981) Die Wirkung von IS-5-MN bei koronarer Herzkrankheit. Med Welt 32:554PubMedGoogle Scholar
- 2.Müller G, Hacker W, Schneider B (1983) Intra-individual comparison of the action of equal doses of isosorbide-5-endomononitrate, slow-release isosorbide dinitrate and placebo in patients with coronary heart disease. Klin Wochenschr 61:409PubMedCrossRefGoogle Scholar
- 3.Evans W, Heyle C (1953) Comparative value of drugs used in the continuous treatment of angina pectoris. Quart J Med 2:311Google Scholar
- 4.Aronow WS, Chesluk HM (1970) Sublingual isosorbide dinitrate therapy vs sublingual placebo in angina pectoris. Circulation 41:869PubMedGoogle Scholar
- 5.Goldstein RE, Reswig DR, Redwood DR, Beiser GD, Epstein SD (1971) Clinical and circulatory effects of isosorbide dinitrate. Circulation 43:629PubMedGoogle Scholar
- 6.Sociedad Argentina de Cardiologia (1981) Consejo de ergometria y rehabilitation. Recomenda-ciones para la práctica normalizada de ergometria. Buenos AiresGoogle Scholar
- 7.Ellestad MH, Allen W, Wan MCK, Kemp GL (1969) Maximal tradmill stress testing for cardiovascular evaluation. Circulation 39:517PubMedGoogle Scholar
- 8.Stoltz FJ, Rohac JM (1975) Reproducibility of exercise tests in patients with symptomatic ischemic heart disease. Br Heart J 37:785CrossRefGoogle Scholar
- 9.Fucks RM, Erinker JA, Maugham WL, Weidfeldt MJ, Kin FC (1981) Coronary flow limitation during the development of ischemia. Effect of atrial pacing in patients with left anterior descendent coronary disease. Am J Cardiology 48:1029CrossRefGoogle Scholar
- 10.De Servi S, Specchia G, Falcone C, Gravazzi A, Mussini A, Angioli L, Bramucci E, Ardissino D, Vaccari L, Salerno J, Bobba P (1983) Variable threshold exertional angina in patients with transient vasoespastic myocardial ischemia with respect to exercise test results and therapeutic implications. Am J Cardiology 51:397CrossRefGoogle Scholar
- 11.Mehmel HC, Ruffmann K, Schwarz F, Manthey J, Kübier W (1981) Die Wirkung von Isosor-bid-5-Mononitrat (IS-5-MN) auf die linksventrikuläre Hämodynamik.Google Scholar
- 12.Biamino GM, Oeff D, Andresen HJ, Lichey E, Prokein R, Arntz, v. Leitner E, Schröder R (1981) Hämodynamische Effekte von Isosorbid-5-Mononitrat unter Ruhe- und Belastungsbedingungen bei Patienten mit schwerer Angina pectoris. Med Welt 32:535PubMedGoogle Scholar
- 13.Bödigheimer K, Nowak FG, Delius W (1981) Vergleichende invasive Untersuchung von Isosor-bid Mononitrat und Isosorbid Dinitrat. Med Welt 32:543PubMedGoogle Scholar
- 14.Sarnoff SJ, Braunwald E, Welch GH (1958) Hemodynamic determinants of oxygen Consumption of the heart, with special reference to the tension-time index. Am J Physiol 192:148PubMedGoogle Scholar
- 15.Grobel FL, Nordstrom LA, Nelson RR, Vorganse CR, Wang Y (1978) The rate pressure product as an index of myocardial oxygen consumption during exercise in patients with angina pectoris. Circulation 57:349Google Scholar
- 16.Robinson BF (1967) Relation of heart rate and systolic blood pressure to the onset of pain in angina pectoris. Circulation 35:1073PubMedGoogle Scholar
- 17.deAptecar F, Aptecar M, Vázquez A, Dell Arsiprete CF (1981) Respuesta Cardiovascular al Esfuerzo en el Hombre Sano. Estudio Sistemático de las Variables Fisiológicas. Rev Arg Cardiologia 49: Suppl 1Google Scholar
- 18.Tabakin BS, Hanson JS, Messiam TW, Candvell GJ (1964) Hemodynamic response of normal men to graded treadmill excercise. J Appl Physiol 19:457PubMedGoogle Scholar
- 19.Gregg DE, Fisher LC (1963) Blood supply to the heart. In: Hamilton WF, Dow P. Handbook of Physiology, Soc 2. Circulation. American Physiological Society, WashingtonGoogle Scholar
- 20.Wilmore JH (1977) Acute and chronic physiological responses to exercise in cardiovascular health and disease. Amsterdam EA, Wilmore J, De Maria H (eds) York Medical Books, New YorkGoogle Scholar
- 21.Ellestad MH, Allen W, Wan MCK, Kemp GI (1969) Maximal treadmill stress testing for cardiovascular evaluation. Circulation 39:517PubMedGoogle Scholar
- 22.Foster GL, Reeves J, Meade JH (1966) Hemodynamic responses to exercise in clinically normal middle age men and in those with angina pectoris. J Clin Invest 43:1758CrossRefGoogle Scholar
- 23.Forman R, Eng C, Kirk ES (1983) Comparative effect of verapamil and nitroglycerin on collateral blood flow. Circulation 67:1204CrossRefGoogle Scholar
- 24.Wagniart P, Ferguson RI, Chaitman BR, Achard F, Benacerraf A, Delanguenhagen B, Morin B, Pasternac A, Bourasa M (1982) Increased exercise tolerance and reduced electrocardiography ischemia with diltiazen in patients with stable angina pectoris. Circulation 66:23PubMedCrossRefGoogle Scholar
- 25.Chaitman BR, Wagniart P, Pasternac A, Brevers G, Scholl JM, Lam J, Methe M, Ferguson RJ, Bourassa MG (1984) Improved exercise tolerance after propranolol, diltiazem or nifedipine in angina pectoris: comparison at 1, 3 and 8 hours and correlation with plasma drug concentration. Am J Cardiology 53:1CrossRefGoogle Scholar
- 26.Detry JM, Bruce RA (1971) Effects of physical training on exertional ST segment depression in coronary heart disease. Circulation 44:390PubMedGoogle Scholar
- 27.Redwood DR, Rosing DR, Godstein RE, Beiser GD, Epstein SE (1977) Importance of the design of an exercise protocol in the evaluation of patients with angina pectoris. Circulation 43:618Google Scholar
Copyright information
© Springer-Verlag Berlin Heidelberg 1985