Genetics and Cytogenetics of Klinefelter’s Syndrome

  • K. D. Zang
Conference paper

Abstract

In 1942 Klinefelter, Reifenstein, and Albright published an article on a syndrome “characterized by gynecomastia, aspermatogenesis without a-Leydi-gism, and increased excretion of follicle-stimulating hormone”. Although Ber-blinger had described a combination of similar clinical symptoms some years previously (1934), Klinefelter et al. were the first to define out of the large and heterogeneous group of primary male hypogonadism a syndrome whose delineation from the other forms and whose nosological homogeneity appeared convincing. Today a definite classification is given by the cytogenetic characterization.

Keywords

Meiotic Division Klinefelter Syndrome Gonadal Dysgenesis Barr Body Normal Segregation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1984

Authors and Affiliations

  • K. D. Zang
    • 1
  1. 1.Institut für HumangenetikUniversität des Saarlandes, UniversitätsklinikenHomburg/SaarGermany

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