The Colloid-Crystalloid Controversy of Fluid Resuscitation

Abstract

Over 80% of cases of shock seen in general hospital practice are due primarily to depletion of intravascular volume, and prompt correction of the volume deficit following blood, plasma, or fluid loss is likely to be curative. Even in patients with cardiogenic shock due to myocardial infarction intravascular volume may be depleted, owing in part to excessive venoconstriction. However, if distributive defects underlie the shock state, owing to bacteremia, autonomic blockade, or intoxication with narcotics, sedatives, or tranquilizers, the intravascular capacity is extended.