Inhalationsanaesthesie heute und morgen pp 135-141 | Cite as
Einfluß von Halothan und Enfluran auf die Mikrozirkulation
Chapter
Zusammenfassung
Halothan wird seit 1956 als volatiles Anaesthetikum verbreitet eingesetzt [3]. Enfluran kommt seit 1962 als echte Alternative zur Anwendung [8]. Gute Steuerbarkeit, rasches Erwachen und eine geringe Inzidenz von Nebenwirkungen sind die wichtigsten Vorteile dieser Anaesthetika. Während die Wirkungen von Halothan und Enfluran auf die zentrale Hämodynamik gut untersucht sind, liegen nur wenige Informationen über die Beeinflussung der Mikrozirkulation und über Veränderungen der Versorgung des Gewebes mit Sauerstoff und Substraten vor.
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Literatur
- 1.Akester JM, Brody MJ (1969) Mechanism of vascular resistance changes produced in skin and muscle by halo thane. Pharmacol Exp Ther 170: 287Google Scholar
- 2.Chien S (1967) Role of sympathetic nervous system in shock. Physiol Rev 47: 214PubMedGoogle Scholar
- 3.Deutsch S, Linde HW, Dripps RD (1962) Circulatory and respiratory actions of halo thane in normal man. Anaesthesiology 23: 631CrossRefGoogle Scholar
- 4.Endrich B, Asaishi K, Goetz A, Meßmer K (1980) Technical report. A new chamber technique for microvascular studies in unanaesthetized animals. Res Exp Med (Berl) 177: 125CrossRefGoogle Scholar
- 5.Fronek A, Witzel T (1974) Haemodynamics of terminal vascular bed in canine haemorrhagic shock. Surgery 75: 408PubMedGoogle Scholar
- 6.Fung YC (1973) Stochastic flow in capillary blood vessels. Microvasc Res 5: 34PubMedCrossRefGoogle Scholar
- 7.Grega GJ, Schwinghammer JM, Haddy FJ (1971) Changes in forelimb weight and segmental resis-tances following severe haemorrhage. Circ Res 29: 691PubMedGoogle Scholar
- 8.Hudon F, Jacques A, Dery R (1963) Respiratory and haemodynamic effects of enflurane anaesthesia. Can Anaesth Soc J 10: 442PubMedCrossRefGoogle Scholar
- 9.Intaglietta M, Tompkins WR (1973) Microvascular measurements by video image shearing and splitting. Microvasc Res 5: 309PubMedCrossRefGoogle Scholar
- 10.Intaglietta M, Silverman NR, Tompkins WR (1975) Capillary flow velocity measurements in vivo and in situ by television method. Microvasc Res 10: 165PubMedCrossRefGoogle Scholar
- 11.Kessler M, Grunewald M (1969) Possibilities of measuring oxygen pressure fields in tissue by multi-wire platinum electrodes. Prog Respir Res 3: 147Google Scholar
- 12.Longnecker DE, Harris PD (1972) Dilatation of small arteries and veins in the bat during halothane anaesthesia. Anaesthesiology 37: 432CrossRefGoogle Scholar
- 13.Luebbers DW (1969) Principle of construction and application of various platinum electrodes. Prog Respir Res 3: 136Google Scholar
- 14.McHugh RD, Epstein RM, Longnecker DE (1979) Halothane mimics oxygen in oxygen mieroeleetrodes. Anaesthesiology 50: 47CrossRefGoogle Scholar
- 15.Miller ED, Kistner JR, Epstein RM (1979) Distribution of blood flow with anaesthetics. Anaesthesiology 51: 124CrossRefGoogle Scholar
- 16.Schmid-Schoenbein GW, Zweifach BW, Kovalcheck S (1977) The application of stereological principles to morphometry of the microcirculation in different tissues. Microvasc Res 14: 303PubMedCrossRefGoogle Scholar
- 17.Swan H (1965) Experimental acute haemorrhage. Arch Surg 91: 390PubMedGoogle Scholar
- 18.Yamaki T, Baez S, Feldman SM, Gootman PM, Orkin LR (1978) Microvascular responses to norepinephrine and vasopressin during halothane anaesthesia in the rat. Anaesthesiology 48: 332CrossRefGoogle Scholar
- 19.Zawicki DF, Jain RK, Schmid-Schoenbein GW, Chien S (1981) Dynamics of neovascularization in normal tissue. Microvasc Res 21: 27PubMedCrossRefGoogle Scholar
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