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Amantadine and Its Derivatives

  • J. L. Schulman
Chapter
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 61)

Abstract

Amantadine hydrochloride (1-adamantanamine hydrochloride) was the first antiviral chemotherapeutic agent (1966) to be licensed for general use in the United States. However, despite the demonstrated efficacy of this compound in the prophylaxis (and more recently in the treatment) of influenza A virus infections, it has never been widely employed and its recommended use remains the subject of considerable controversy (Sabin 1978).

Keywords

Influenza Virus Influenza Virus Infection Rubella Virus Influenza Virus Replication Amantadine Hydrochloride 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • J. L. Schulman

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