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The Immunopathogenesis of Chronic HBV Induced Liver Disease

  • Gary A. Levy
  • Francis V. Chisari
Chapter

Abstract

The pathogenesis of hepatitis B virus induced liver disease is not well understood. Because a suitable animal model and methods for in vitro propagation of hepatitis B virus (HBV) have not been available, most current information is derived from clinical studies. Although considerable circumstantial evidence suggests the involvement of immunologic mechanisms [61] it is difficult to determine if the reported immunologic events are primary pathogenetic determinants or merely secondary to the disease.

Keywords

Chronic Active Hepatitis Hepatocellular Injury Chronic Active Liver Disease Suppressor Cell Activity Cytotoxic Effector Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • Gary A. Levy
    • 1
  • Francis V. Chisari
    • 1
  1. 1.Department of Molecular Immunology and Clinical ResearchResearch Institute of Scripps ClinicLa JollaUSA

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