Effect of Verapamil on Left Ventricular Isovolumic Relaxation Time and Regional Left Ventricular Filling in Hypertrophic Cardiomyopathy

  • Peter Hanrath
  • Detlef G. Mathey
  • Peter Kremer
  • Frank Sonntag
  • Walter Bleifeld
Conference paper

Abstract

Hypertrophic obstructive and nonobstructive cardiomyopathy are often associated with an abnormal prolonged left ventricular isovolumic relaxation time and a disturbed left ventricular filling pattern [1–5]. Recent experimental studies revealed that calcium antagonists may improve impaired left ventricular relaxation caused by ischemia or hypoxia [6, 7]. Based on these experimental results, it was the purpose of the present study to examine whether the impaired left ventricular relaxation in patients with obstructive and nonobstructive hypertrophic cardiomyopathy can be improved by intravenous application of verapamil.

Keywords

Hypertrophic Cardiomyopathy Left Ventricular Filling Left Ventricular Relaxation Ventricular Relaxation Isovolumic Relaxation Time 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • Peter Hanrath
  • Detlef G. Mathey
  • Peter Kremer
  • Frank Sonntag
  • Walter Bleifeld

There are no affiliations available

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