Geriatrics 2 pp 202-221 | Cite as

The Kidney

  • L. Sourander
Chapter

Abstract

Kidney diseases in the aged are the same as in younger age groups, but the process of aging modifies their clinical presentation. Clinical signs of kidney disease in the aged often differ from signs of these diseases in younger patients, depending on an altered somatic response to disease in advanced age and the simultaneous occurrence of age-induced changes in the kidneys.

Keywords

Urinary Tract Infection Nephrotic Syndrome Continuous Ambulatory Peritoneal Dialysis Indwell Catheter Renal Plasma Flow 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Arieff AJ, Anderson RJ, Massry SG (1971) Acute glomerulonephritis in the elderly. Geriatrics 26:74–84PubMedGoogle Scholar
  2. Arieff A, Anderson RJ, Massry SG (1973) Acute glomerulonephritis in the elderly. Mod Geriatrics 3:77Google Scholar
  3. Asscher AW (1980) The challenge of urinary tract infections. Academic Press, London Toronto Sydney, Grune & Stratton, New York San Francisco, p 41Google Scholar
  4. Baehler RW, Galla JH (1976) Conservative management of chronic renal failure. Geriatrics 31:46–50Google Scholar
  5. Bartecchi CE (1975) When should peritoneal dialysis be considered in elderly patients? Geriatrics 30:47–51PubMedGoogle Scholar
  6. Baumannis J, Russell HK (1959) Pyelonephritis in a chronic disease hospital. Geriatrics 14:25Google Scholar
  7. Bengtsson U, Hogdahl A, Hood B (1968) Chronic non-obstructive pyelonephritis and hypertension: a long term study. Q J Med 37:361–377PubMedGoogle Scholar
  8. Berlyne GM, Baker SB, De C (1964) Acute anuric glomerulonephritis. Q J Med 33:105–115PubMedGoogle Scholar
  9. Binet L, Laroche C, Mathé G (1952) Contribution a l’etude du rein sénile. Presse méd 60:1211–1212PubMedGoogle Scholar
  10. Boswell DC, Eknovan G (1968) Acute glomerulonephritis in the aged. Geriatrics 23:73–80PubMedGoogle Scholar
  11. Brocklehurst JC (1971) The urinary tract. In: Rossman I (ed) Clinical Geriatrics. J. B. Lip-pincott Company, p 220Google Scholar
  12. Brocklehurst JC (1977) Urinary infections: Not all patients need treatment. Mod Geriatrics 7:33–36Google Scholar
  13. Brocklehurst JC, Brocklehurst S (1978) The management of indwelling catheters. Brit J Urol 50:102–105PubMedCrossRefGoogle Scholar
  14. Brocklehurst JC, Dillane JB, Griffiths L, Fry J (1968) The prevalence and symptomatology of urinary infection in an aged population. Geront Clin 10:242–253PubMedCrossRefGoogle Scholar
  15. Brocklehurst JC, Bee P, Jones D, Palmer M (1977) Bacteriuria in geriatric hospital patients: its correlates and management. Age and Ageing 6:240–245PubMedCrossRefGoogle Scholar
  16. Brod J (1968) Changes of renal function with age. Scr Med Fac Med Brun 41:223–229Google Scholar
  17. Bruckel RW, Wincker HJ (1963) Clinical aspects of urinary tract infections in geriatrics. Exc Med Congr Ser 57Google Scholar
  18. Carty M, Brocklehurst JC, Carty J (1981) Bacteriuria and its correlates in old age. Gerontology 27:72–75PubMedCrossRefGoogle Scholar
  19. Cattell WR, Charlton CAC, McSherry A, Kelsey Fry J, O’Grady F (1973) The localization of urinary tract infection and its relationship to relapse, reinfection and treatment. In: Brumfitt W, Asscher AW (eds) Urinary tract infection. Oxford University Press, London, p 206Google Scholar
  20. Conner JF, Coleman SE, Davis JL, McGaughey FS (1968) Bacterial 1-forms from urinary-tract infections in a veterans’ hospital population. J Amer Geriatrics Soc 16:893–900Google Scholar
  21. Cox OE, Hinman F Jr (1965) Factors in resistance to infection of the bladder. In: Kass EH (ed) Progress in pyelonephritis, F. A. Davis, Philadelphia, p 563Google Scholar
  22. Darmady EM (1974) Transplantation and the ageing kidney. Lancet 2:1046–1049PubMedCrossRefGoogle Scholar
  23. Darmady EM, McIver AG (1980) Renal Pathology, Butterworths, London BostonGoogle Scholar
  24. Darmady EM, Offer J, Woodhouse MA (1973) The parameters of the aging kidney. J Pathol 109:195–209PubMedCrossRefGoogle Scholar
  25. Davidson AJ, Talner LB, Sowns III WM (1969) A study of the angiographic appearance of the kidney in aging normotensive population. Radiology 92:975–983PubMedGoogle Scholar
  26. Davies DF, Shock NW (1950) Age changes in glomerular filtration rate, effective renal plasma flow and tubular excretory capacity in adult males. J Clin Invest 29:497–507Google Scholar
  27. Derot M, Faye C (1956) Le réin sénile. Gaz med Fr 63:195–199PubMedGoogle Scholar
  28. Dontas AS, Kasviki-Charvati P (1976) Significance of diuresis-provoked bacteriuria. J Inf Dis 134:174–180CrossRefGoogle Scholar
  29. Dontas AS, Papanayiotou P, Marketos S, Papanicolaou N, Economou P (1966) Bacteriuria in old age. Lancet 2:305–306PubMedCrossRefGoogle Scholar
  30. Dontas AS, Papanayiotou P, Marketos S, Papanicolaou N (1968) The effect of bacteriuria on renal function patterns in old age. Clin Sci 34:73–81PubMedGoogle Scholar
  31. Dontas AS, Rasviki-Charvati P, Chem L, Papanayiotou PC, Marketos SG (1981) Bacteriuria and survival in old age. N Engl J Med 304:939–943PubMedCrossRefGoogle Scholar
  32. Epstein M, Hollenberg NK (1976) Age as a determinant of renal sodium conservation in normal man. J Lab Clin Med 87:411PubMedGoogle Scholar
  33. Esposito AS, Gleckman RA, Cram S, Crowley M, McCabe F, Drapkin MS (1980) Community-acquired bacteremia in the elderly: analysis of one hundred consecutive episodes. J Amer Geriatrics Soc 28:315–319Google Scholar
  34. Fairley RF, Carson NE, Gutch RC, Leighton P, Grounds AD, Laird EC, McCallum PHG, Sleeman RL, O’Keefe CM (1971) Site of infection in acute urinary tract infections in general practice. Lancet 2:615PubMedCrossRefGoogle Scholar
  35. Fawcett IW, Hilton PJ, Jones NF, Wing AJ (1971) Nephrotic syndrome in the elderly. Brit Med J 2:387–388PubMedCrossRefGoogle Scholar
  36. Feingold DS (1969) Biology and pathogenicity of microbial spheroplasts and L-forms. N Engl J Med 281:1159–1170PubMedCrossRefGoogle Scholar
  37. Fenton SAA, McCready W, Cattran DC, Oreopoulos, DG, Whiteside C (1980) Selected clinical aspects of continuous ambulatory dialysis. In: Legrain M (ed) Continuous ambulatory peritoneal dialysis proceedings of an international symposium. Excerpta Medica Amsterdam, pp 107–112Google Scholar
  38. Finkelstein FO, Hayslett JP (1976) Nephrotic syndrome: Etiology, diagnosis and treatment. Geriatrics 31:39–48PubMedGoogle Scholar
  39. Freedman LR (1967) Chronic pyelonephritis at autopsy. Ann Intern Med 66:697–710PubMedGoogle Scholar
  40. Grüneberg RN, Bendall MJ (1979) Hospital outbreak of trimehoprim resistance in pathogenic coliform bacteria. Br Med J 2:7–9PubMedCrossRefGoogle Scholar
  41. Guttmann LT, Turck M, Petersdorf RG, Wedgwood RJ (1965) Significance of bacterial variants in urine of patients with chronic bacteriuria. J Clin Invest 44:1945–1952CrossRefGoogle Scholar
  42. Herbeuvall R (1961) Physiopathologie rénale chez le sujet âgé. Schweiz Med Wochenschr 91:1386–1390Google Scholar
  43. Hollenberg NR (1974) Senescence and the renal vasculature in normal men. Circ Res 34:309PubMedGoogle Scholar
  44. Howell TH, Piggot AP (1948) Kidney in old age. J Geront 3:124–128PubMedGoogle Scholar
  45. Huovinen P, Mäntyjärvi R, Toivanen P (1982) Trimethoprim resistance in hospitals. Brit Med J 284:782–787CrossRefGoogle Scholar
  46. Källenius G, Winberg J (1978) Bacterial adherence to periurethral epithelial cells in girls prone to urinary tract infections. Lancet 2:540PubMedCrossRefGoogle Scholar
  47. Kasanen A (1982) Status and use of trimethoprim in urinary tract infections. Farmos Med News 1:17–22Google Scholar
  48. Kass EH (1955) Chemotherapeutic and antibiotic drugs in management of infection of urinary tract. Am J Med 18:746–781Google Scholar
  49. Kassirer J (1969) Atheroembolic renal disease. N Engl J Med 280:812PubMedCrossRefGoogle Scholar
  50. Kaye M, Pajel PA, Somerville PJ (1982) Continuous ambulatory peritoneal dialysis in the elderly. Lancet 2:270–271PubMedCrossRefGoogle Scholar
  51. Kirkland JL, Robinson JM (1981) Bacteriuria and survival in old age. N Engl J Med 305: 586–587PubMedGoogle Scholar
  52. Kjellstrand CM, Shideman JR, Lynch RE, Buselmeier TJ, Simmons RL, Najarian JS (1976) Kidney transplants in patients over 50. Geriatrics 31:65–73PubMedGoogle Scholar
  53. Kumar R, Hill CM, McGeown MG (1973) Acute renal failure in the elderly. Lancet 1:90PubMedCrossRefGoogle Scholar
  54. Lee HA, Stirling G, Scharpstone P (1966) Acute glomerulonephritis in middle-aged and elderly patients. Br Med J 2:1361–1363PubMedCrossRefGoogle Scholar
  55. Ljungqvist A, Lagergren C (1962) Normal intra-renal arterial pattern in adult and aging human kidney. J Anat 26:285Google Scholar
  56. Marketos SG, Papanayiotou P, Dontas AS (1969) Bacteriuria and non-obstructive renovascular disease in old age. J Geront 23:33–36Google Scholar
  57. Marketos SG, Dontas AS, Papanayiotou P, Economou P (1970) Bacteriuria and arterial hypertension in old age. Geriatrics 25:136–146PubMedGoogle Scholar
  58. Montoliu J, Darnell A, Torras A, Revert L (1981) Acute and rapidly progressive forms of glomerulonephritis in the elderly. J Amer Geriatrics Soc 29:108–116Google Scholar
  59. Moore RA (1931) Total number of glomeruli in the normal human kidney. Anat Rec 50:709Google Scholar
  60. Nesson HR, Robbins SL (1960) Glomerulonephritis in older age groups. Archs Int Med 105:47–56Google Scholar
  61. Norberg B, Norberg A, Parkhede U, Gippert H (1979) Effect of short-term high-dose treatment with methenamine hippurate on urinary infection in geriatric patients with an indwelling catheter. IV. Clinical evaluation. Swe-Eur J Clin Pharmacol 15:357–361CrossRefGoogle Scholar
  62. Oliver J (1952) Urinary system In: Cowdry EW (ed) Problems of aging Williams & Wilkins, BaltimoreGoogle Scholar
  63. Oreopoulos DG (1980) Introductory remarks: selection criteria and clinical results continuous ambulatory peritoneal dialysis. In: Legrain M (ed) Continuous ambulatory peritoneal dialysis. Proceedings of an International Symposium. Excerpta Medica Amsterdam, pp 101–106Google Scholar
  64. Parvinen M, Sourander LB, Vuorinen P (1965) Cystographic studies of old women. Geront Clin 7:343–347PubMedCrossRefGoogle Scholar
  65. Popovich RP, Moncrief JW, Noloh KD, Ghods AJ, Twardowski LJ, Pyle WK (1980) Continuous ambulatory peritoneal dialysis. Am Intern Med 88:449–456Google Scholar
  66. Price JDE, Moriarty MV (1980) Continuous ambulatory peritoneal dialysis: selection criteria - failures and causes - deaths - diabetes mellitus. In: Legrain M (ed) Continuous ambulatory peritoneal dialysis proceedings of an international symposium. Excerpta Medica Amsterdam, pp 113–119Google Scholar
  67. Ralston AJ (1975) Renal disease, Modern Geriatrics 5:10–14Google Scholar
  68. Reynes M, Caulet T, Diebold J (1968) Microvascularisation du réin normal et senescent. Path Biol 16:1081–1089Google Scholar
  69. Roessle R, Roulet F (1932) Maß und Zahl in der Pathologie. Springer, Berlin Heidelberg New York, p 63Google Scholar
  70. Seneca H, Grant JP, Jr (1976) Urologie sepsis/shock. J Am Geriat Soc 24:292–300 Shimada K (1960) Microbiometrical and histological studies on physiological changes of human kidney according to age. Sapporo Med J 17:319Google Scholar
  71. Shock NW (1946) Kidney function tests in aged males. Geriatrics 1:232–239PubMedGoogle Scholar
  72. Shock NW (1952) In: Cowdry (ed) Problems of ageing Williams & Wilkins, Baltimore, p 614Google Scholar
  73. Shock NW (1968) The physiology of aging. In: Powers JH (ed) Surgery of the aged and debilitated patients. Saunders, London, p 17Google Scholar
  74. Shock NW, Andres R, Norris AH, Tobin JD (1979) Patterns of longitudinal changes in renal function. In: Orimo H, Shimada K, Iriki M, Maeda D (ed) Recent advances in gerontology. International congress series 469 Excerpta Medica, Amsterdam Oxford Princeton, pp 525–527Google Scholar
  75. Sourander LB (1966) Urinary tract infection in the aged. An epidemiological study. Ann Med Int Fenniae 55, suppl 45Google Scholar
  76. Sourander LB, Kasanen A (1972) A 5-year follow-up of bacteriuria in the aged. Geront Clin 14:274–281PubMedCrossRefGoogle Scholar
  77. Sourander L, Saarimaa H (to be published) Septicaemia in geriatric hospital patientsGoogle Scholar
  78. Sourander LB, Ruikka I, Grönroos M (1965) Correlation between urinary tract infection, prolapse conditions and function of the bladder in aged female hospital patients. Geront Clin 7:179–184PubMedCrossRefGoogle Scholar
  79. Sourander L, Kasanen A, Pasternack A, Kaarsalo E (1979) Uraemia in the aged in South-Western Finland. A longitudinal study. In: Orimo H., Shimada K, Iriki M, Maeda D (eds) Recent advances in gerontology. International congress series 469 Excerpta Medica, Amsterdam Oxford Princeton, pp 540–546Google Scholar
  80. Sourander L, Järvinen H, Juva K (to be published) A longitudinal study of bacteriuria and bacterial resistance in a geriatric hospitalGoogle Scholar
  81. Stamey TA, Sexton CC (1975) The role of vaginal colonization with enterobacteriaceae in recurrent urinary infections. J Urol 113:214PubMedGoogle Scholar
  82. Svanborg-Eden C (1978) Attachment of Escherichia coli to human urinary tract epithelial cells. Scand J Inf Dis Suppl 15Google Scholar
  83. Takazura E (1972) Intrarenal vascular changes with age and disease. Kidney Int 2:224CrossRefGoogle Scholar
  84. Tenckhoff H, Schechter H (1968) A bacteriologically safe peritoneal access device. Trans Am Soc Artif Intern Organs 14:131–137Google Scholar
  85. Zollinger HU (1966) Niere und ableitende Harnwege. In: Doerr W (ed) Spezielle pathologische Anatomie. Springer, Berlin Heidelberg New York, p 116Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1983

Authors and Affiliations

  • L. Sourander

There are no affiliations available

Personalised recommendations