Chemoreception in the Carotid Body pp 86-91 | Cite as
Reaction of Cultured Carotid Body Cells to Different Concentrations of Oxygen and Carbon Dioxide
Conference paper
Abstract
Measurements of tissue PO2 in the cat carotid body performed by Acker, Lubbers, and Purves (1) showed that, compared to other organs, the oxygen tension is relatively low. They found that 79% of the values were below 40 mmHg. Weigelt (9) reported even lower PO2 values with a maximum at 5 mmHg for the rabbit carotid body. We therefore decided to investigate whether and to what extent the oxygen concentration influences the differentiation of isolated carotid body cells in tissue cultures. We cultured the cells in monolayer under both hypoxic and hypercapnic conditions.
Keywords
Carotid Body Glomus Cell Catecholamine Content Bonic Anhydrase Hypercapnic Condition
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References
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© Springer-Verlag Berlin · Heidelberg 1977