Metamorphosis of the Tissue Surface by Progestational Agents

Abstract

The influence of progestogens on the tissue surface structure of the female reproductive tract is exemplified by the series of micrographs shown in Plates 7.1 to 7.9. Progestogens are widely used as constituents of combined hormonal contraceptives as well as alone; the latter regimen is frequently used in daily mini-dosages (“mini-pill”). Recently, IUD’s have become available in combination with progestogens. The daily release of progestogens from an IUD inserted into the uterus promotes the contraceptive effect of the device by transforming the endometrium into a tissue not suitable for implantation of a blastocyst.