Abstract
A wide variety of tissues undergo a change of functional state on exposure to noradrenaline or adrenaline. Those molecular constituents of the effector cells of a tissue with which molecules of these catecholamines must first interact in order to produce a change of state — or response — of the tissue, are the so-called adrenoceptors (also commonly called adrenergic receptors). For convenience, we refer to noradrenaline, adrenaline and other agents which produce responses in tissues by interacting with adrenoceptors, as adrenergic agonists. An agent which specifically inhibits a response produced by an adrenergic agonist is referred to as adrenergic blocking agent or adrenergic antagonist.
This work was supported in part by grants from the USPHS (HE-05237), the Life Insurance Medical Research Foundation, and the New York Heart Association.
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Furchgott, R.F. (1972). The Classification of Adrenoceptors (Adrenergic Receptors). An Evaluation from the Standpoint of Receptor Theory. In: Blaschko, H., Muscholl, E. (eds) Catecholamines. Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology, vol 33. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65249-3_9
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DOI: https://doi.org/10.1007/978-3-642-65249-3_9
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