Connective Tissues pp 89-101 | Cite as
The Subcellular Site of the Biosynthesis of N-Glycoloyl- and N-Acetyl-O-Acetylneuraminic Acid Components of Porcine, Bovine and Equine Submaxillary Gland Glycoproteins
Chapter
Abstract
Acylneuraminic acids bound to glycoproteins and to gangliosides are widely distributed in cells and fluids of animals. As their biological functions are manifold (Gottschalk, 1972), they have gained the interest of many chemists and physiologists in the last years. Acylneuraminic acids, which have been called “sialic acids” by Blix et al. (1957), contain acyl residues bound to the amino-group and in some cases also to the hydroxyl groups. The best known and most widely distributed sialic acid is N-acetylneuraminic acid, systematically named β-D (-)-5-acetamido-3, 5-dideoxy-D-glycero-D-galacto-nonulosaminic acid (Fig. 1).
Keywords
Sialic Acid Submaxillary Gland Specific Radioactivity Neuraminic Acid Cytosole Compartment
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