Replication: Arrest of Prokaryotic DNA Replication

  • Ellen L. Zechner
Part of the Progress in Botany/Fortschritte der Botanik book series (BOTANY, volume 58)

Abstract

DNA replication can be separated into three distinct steps: initiation at an origin of replication, elongation, and termination. The vast majority of studies of DNA replication in prokaryotic and eukaryotic systems have been dedicated to understanding the nature and regulation of the events occurring at replication origins and to characterizing established elongating replication forks. In recent years, interest in termination of replication in prokaryotic systems has increased because of the potential role of this process as a coordinating link between the conclusion of a cycle of DNA replication and the onset of cell division. In E. coli cells, DNA replication initiates at a unique origin, oriC, and proceeds bidirectionally around the circular chromosome. The opposing replication forks meet roughtly 180° away from oriC in the terminus region, terC (Bird et al. 1972; Prescott and Kuempel 1972).

Keywords

Replication Fork Inverted Repeat Region Replication Arrest Helicase Assay Replication Terminus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • Ellen L. Zechner
    • 1
  1. 1.Institut für MikrobiologieKarl-Franzens-Universität GrazGrazAustria

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