Temperature-Sensitive Magnetic Resonance Sequences

  • U. Sinha
  • S. Sinha
  • T. Oshiro


The introduction of the open-magnet configuration with wide-angle accessibility to the patient and real-time monitoring of images within the scanner room has sparked considerable interest in magnetic resonance (MR) guided interventional procedures. Such procedures, including MR-guided biopsies, hyperthermia, cryoablation, and ablation using laser, radiofrequency (RF), and focused ultrasound (FUS), have been performed both in conventional 1.5-T scanners (closed configuration) and at low fields (open and closed configurations) [1–6]. A critical part of MR- guided ablation procedures is the ability to monitor spatially localized changes in temperature using heat-sensitive MR pulse sequences. An important area of MR-guided interventional procedures is the thermal ablation by laser-induced thermotherapy (LITT), FUS, and RF techniques. MR imaging is unique in its ability noninvasively to measure the distribution of spatial temperature through the effect of temperature on MR parameters (T1, diffusion, and proton chemical shift). The demands on temporal resolution are high, although not necessarily requiring real-time frame rates as in tracking of MR-guided procedures. The ablations typically are in the range of 20–40 s for FUS, 1–2 min for RF, and 10–20 min for LITT.


Apparent Diffusion Coefficient Magn Reson Image Signal Intensity Variation Contrast Agent Uptake Magnetic Resonance Thermometry 
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© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • U. Sinha
  • S. Sinha
  • T. Oshiro

There are no affiliations available

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