Severe Head Injury in Patients with Multiple Trauma

  • J. Albanèse
  • M. Léone
  • C. Martin
Conference paper
Part of the Yearbook of Intensive Care and Emergency Medicine 2001 book series (YEARBOOK, volume 2001)

Abstract

Severe head trauma is a major cause of death and disability in young adults. While it is sometimes an isolated injury, it is often part of multiple trauma. The specificity of head trauma compared with other extracranial injuries is expressed by its contribution to the cause of death in trauma patients; it is responsible for 68% of the deaths [1, 2]. Indeed, when it is not associated with hemorrhagic shock, multiple trauma mortality depends uniquely on the severity of the initial intracranial injury [3]. On the other hand, the association of trauma with shock is responsible for a very high rate of mortality [4] as well as a worsening of the neurological prognosis [5]. Thus, sequelae that are sometimes very severe, make social-economic rehabilitation impossible for the patient. While, in certain cases, death or sequelae are inevitable, in other cases they can be avoided by early and adapted care [6]. Indeed, one of the best ways to improve the vital and functional prognosis is to limit the extension of secondary cerebral lesions [7–9].

Keywords

Mean Arterial Pressure Glasgow Coma Scale Head Trauma Cerebral Perfusion Pressure Severe Head Injury 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Chesnut RM, Marshall LF (1993) Management of severe head injury. In: Rapper AA (ed) Neurological and Neurosurgical Intensive Care. Raven Press, New York, pp 203–246Google Scholar
  2. 2.
    Maas AIR (1993) Pathophysiology, monitoring and treatment of severe head injury. In: Vincent JL (ed) Yearbook of Intensive Care and Emergency Medicine. Springer-Verlag, Heidelberg, pp 564–578Google Scholar
  3. 3.
    Baltas I, Gerogiannis N, Sakellariou P, Matamis D, Prassas A, Fylaktakis M (1998) Outcome in severely head injured patients with and without multiple trauma. J Neurosurg Sci 42:85–88PubMedGoogle Scholar
  4. 4.
    Heckbert SR, Vedder NB, Hoffman W, et al (1998) Outcome after hemorrhagic shock in trauma patients. J Trauma 45:545–549PubMedCrossRefGoogle Scholar
  5. 5.
    Feldman Z, Gurevitch B, Artru AA, Shapira Y, Reichenthal E (1997) Neurologic outcome with hemorrhagic hypotension after closed head trauma in rats: effect of early versus delayed conservative fluid therapy. J Trauma 43:667–672.PubMedCrossRefGoogle Scholar
  6. 6.
    Stocchetti N, Pagliarini G, Gennari M, et al (1994) Trauma care in Italy: evidence of in-hospital preventable deaths. J Trauma 36:401–405PubMedCrossRefGoogle Scholar
  7. 7.
    Dearden NM (1992) Brain edema and raised intracranial pressure after head injury. In: Vincent JL (ed) Yearbook of Intensive Care and Emergency Medicine. Springer-Verlag, Heidelberg, pp 537–552Google Scholar
  8. 8.
    Cruz J (1993) On-line monitoring of global cerebral hypoxia in acute brain. J Neurosurg 79: 228–261PubMedCrossRefGoogle Scholar
  9. 9.
    Bouma GJ, Muizelaar JP, Bandoh K (1992) Blood pressure and intracranial pressure volume dynamics in severe head injury: relation-ship with cerebral blood flow. J Neurosurg 77:15–24PubMedCrossRefGoogle Scholar
  10. 10.
    Regel G, Lobenhoffer P, Grotz M, Pape HC, Lehmann U, Tscherne H (1995) Treatment results of patients with multiple trauma: an analysis of 3406 cases treated between 1972 and 1991 at a German Level I Trauma Center. J Trauma 38:70–78PubMedCrossRefGoogle Scholar
  11. 11.
    Linnik MD (1995) Programmed cell death in cerebral ischemia. Therapeutic implications. CNS Drugs 4:1–6Google Scholar
  12. 12.
    Miller JD, Sweet RC, Narayan R, Becker DP (1978) Early insults to the injured brain. JAMA 240:439–442PubMedCrossRefGoogle Scholar
  13. 13.
    Piek J, Chesnut R, Marshall L, et al (1992) Extracranial complications of severe head injury. J Neurosurg 77:901–907PubMedCrossRefGoogle Scholar
  14. 14.
    Jones P, Andrews P, Midgley S, et al (1994) Measuring the burden of secondary insults in head injured patients during intensive care. J Neurosurg Anesth 6:4–14Google Scholar
  15. 15.
    Gentleman D, Dearden M, Midgley S, Maclean D (1993) Guidelines for resuscitation and transfer of patients with serious head injury. Br Med J 307:547–552CrossRefGoogle Scholar
  16. 16.
    Rosner MJ, Rosner SD, Johnson AH (1995) Cerebral perfusion pressure: management protocol and clinical results. J Neurosurg 83:949–962PubMedCrossRefGoogle Scholar
  17. 17.
    Carrel M, Moeschler O, Ravussin P, Boulard G (1994) Medicalisation préhospitalière héliportée et agressions cérébrales secondaires d’origine systémique chez les traumatisés crânio-céré-braux graves. Ann Fr Anesth Réanim 13:326–335PubMedCrossRefGoogle Scholar
  18. 18.
    Chesnut RM, Marshall LE, Klauber MR, Blunt BA (1993) The role of secondary brain injury in determining outcome from severe head injury. J Trauma 34:216–221PubMedCrossRefGoogle Scholar
  19. 19.
    Fessler R, Diaz F (1993) The management of cerebral perfusion pressure and intracranial pressure after severe head injury. Ann Emerg Med 22:998–1002PubMedCrossRefGoogle Scholar
  20. 20.
    Bouma J, Muizelaar J, Stringer W, Choi S, Fatouros P, Young H (1992) Ultra-early evaluation of regional cerebral blood flow in severely head-injured patients using xenon-enhanced computerized tomography. J Neurosurg 77:360–368PubMedCrossRefGoogle Scholar
  21. 21.
    Sheinberg M, Kanter J, Robertson C, Constant C, Narayan R, Grossman R (1992) Continuous monitoring of jugular venous oxygen saturation in head-injured patients. J Neurosurg 76: 212–217PubMedCrossRefGoogle Scholar
  22. 22.
    Muizelaar J, Marmarou A, Ward J, et al (1991) Adverse effects of prolonged hyperventilation in patients with severe head injury: a randomized clinical trial. J Neurosurg 75:731–739PubMedCrossRefGoogle Scholar
  23. 23.
    Pfenninger EG, Lindner KH (1991) Arterial blood gases in patients with acute head injury at the accident site and upon hospital admission. Acta Anaethesiol Scand 35:148–152CrossRefGoogle Scholar
  24. 24.
    Graham DI, Ford I, Adam JH (1989) Ischaemia brain damage is still present in fatal non missile head injury. J Neurol Neurosurg Psychiatry 52:346–350PubMedCrossRefGoogle Scholar
  25. 25.
    Teasdale G, Jennet B (1974) Assessment of coma and impaired consciousness. A practical scale. Lancet 2:81–84CrossRefGoogle Scholar
  26. 26.
    Marshall LF, Gautille T, Klauber MR, et al (1991) A new classification of head injury based on computerized tomography. J Neurosurg 75 (suppl): 514–520Google Scholar
  27. 27.
    Lenfant F, Sobraquès P, Nicolas F, Combes JC, Honnart D, Freysz M (1997) Utilisation par des internes d’anesthésie réanimation du score de Glasgow chez le traumatisé crânien. Ann Fr Anesth Réanim 16:39–43Google Scholar
  28. 28.
    Petit P, Bancalari G, Gueugniaud PY (1991) Réanimation préhospitalière et transport du traumatisé. In: XIIe Journées Méditérranéennes d’Anesthésie Réanimation. Sauramps Médical, Marseille, pp 113–134Google Scholar
  29. 29.
    Dakkner RJ, Deeb ZL, Lupetin AR, Rothfus WE (1988) Patterns of high speed impact injury in motor vehicle occupants. J Trauma 28:498–501CrossRefGoogle Scholar
  30. 30.
    Lenfant F, Honnart D, Coudert M, Freysz (1998) Stratégie des examens du polytraumatisé. In: SFAR, Ed Conférences d’actualisation. 40e Congrès National d’Anesthésie et de Réanimation. Paris: Elsevier pp 597–613Google Scholar
  31. 31.
    Brain Trauma Foundation (1996) The role of glucocorticoids in treatment of severe head injury. J Neurotrauma 13:715–723CrossRefGoogle Scholar
  32. 32.
    Anonymous (1997) Prise en charge des traumatisés crâniens grave à la phase précoce. Recommandations pour la pratique clinique. Ann Fr Anesth Réanim 18:1–72Google Scholar
  33. 33.
    Brain Trauma Foundation (1996) The integration of brain-specific treatments in initial resuscitation of severe head injury patient. J Neurotrauma 13:653–660CrossRefGoogle Scholar
  34. 34.
    Brain Trauma Foundation (1996) Indications for intracranial pressure monitoring. J Neurotrauma 13:667–679CrossRefGoogle Scholar
  35. 35.
    Brain Trauma Foundation (1996) Intracranial pressure monitoring technology. J Neurotrauma 13:685–692CrossRefGoogle Scholar
  36. 36.
    Krista LK, Park SN, Morris LM (1998) Intracranial pressure monitor placement by midlevel practitioners. J Trauma 45:884–886CrossRefGoogle Scholar
  37. 37.
    Brain Trauma Foundation (1996) Intracranial pressure treatment threshold. J Neurotrauma 13: 681–684CrossRefGoogle Scholar
  38. 38.
    Bouma GJ, Muizelaar JP, Sung C (1991) Cerebral circulation and metabolism after severe traumatic brain injury: the elusive role of ischaemia. J Neurosurg 75:685–693PubMedCrossRefGoogle Scholar
  39. 39.
    Yoshimo E, Yamaki T, Higachi T (1985) Acute brain edema, in fatal head injury — analysis by dynamic CT scanning. J Neurosurg 63:830–839CrossRefGoogle Scholar
  40. 40.
    Schrader H, Lôfgren J, Zwetnow NN (1985) Influence of blood pressure tolerance to an intracranial expanding mass. Acta Neurol Scand 71:114–126PubMedCrossRefGoogle Scholar
  41. 41.
    Brain Trauma Foundation (1996) Guidelines for cerebral perfusion pressure. J Neurotrauma 13:693–697CrossRefGoogle Scholar
  42. 42.
    Vigué B, Ract C (1998) Monitorage cérébral du traumatisé crânien 40e Congrès National d’Anesthésie et de Réanimation. Elsevier, Paris, pp 383–397Google Scholar
  43. 43.
    Chan KH, Miller JD, Dearden NM (1992) The effects of changes in cerebral perfusion pressure upon middle cerebral artery blood flow velocity and jugular bulb venous oxygen saturation after severe brain injury. J Neurosurg 77:55–61PubMedCrossRefGoogle Scholar
  44. 44.
    Chan KH, Dearden NM, Miller JD, Andrews PJD, Midgley S (1993) Multimodality monitoring as a guide to treatment of intracranial hypertension after severe brain injury. Neurosurg 32: 547–553CrossRefGoogle Scholar
  45. 45.
    Wong FC, Piper IR, Miller JD (1994) Determination of cerebral perfusion pressure thresholds in head injured patients. J Neurol Neurosurg Psychiat 57:1153–1160Google Scholar
  46. 46.
    Cohen JE, Montero A, Israel ZH (1996) Prognosis and chnical relevance of anisocoria-cranioto-my latency for epidural hematoma in comatose patients. J Trauma 41:120–122PubMedCrossRefGoogle Scholar
  47. 47.
    Maas AIR (1996) Guidehnes for management of severe head injury. In: Vincent JL (ed) Yearbook of Intensive Care and Emergency Medicine. Springer-Verlag, Heidelberg, pp 707–715Google Scholar
  48. 48.
    Brain Trauma Foundation (1996) Resuscitation of blood pressure and oxygenation. J Neurotrauma 13:661–666CrossRefGoogle Scholar
  49. 49.
    Siegell JH, Gens DR, Mamantov T, Geisler FH, Goodarzi S, Mackenzie EJ (1991) Effect of associated injuries and blood volume replacement on death, rehabilitation needs, and disability in blunt traumatic brain injury. Crit Care Med 19:1252–1265CrossRefGoogle Scholar
  50. 50.
    Hemmer M (1993) Fluid administration in severe head injury. In: Vincent JL (ed) Yearbook of Intensive Care and Emergency Medicine. Springer-Verlag, Heidelberg, pp 579–587Google Scholar
  51. 51.
    Ogino R, Suzuki K, Kohno M, Nishina M, Kohama A (1998) Effects of hypertonic sahne and dextran 70 on cardiac contractility after hemorrhagic shock., J Trauma 44:59–69PubMedCrossRefGoogle Scholar
  52. 52.
    Chiolero RL, De Tribolet N (1992) Sedatives and antagonists in the management of severely head-injured patients. Acta Neurochir 55 (suppl): 43–49Google Scholar
  53. 53.
    Albanèse J, Martin C (1995) Emergency drug therapy of closed head injury. CNS Drug 3: 337–350CrossRefGoogle Scholar
  54. 54.
    Prielipp RC, Coursin DB (1995) Sedative and neuromuscular blocking drug use in critically ill patients with head injuries. New Horiz 3:456–468PubMedGoogle Scholar
  55. 55.
    Matta B, Menon D (1996) Severe head injury in the United Kingdom and Ireland: a survey of practice and implications for management. Crit Care Med 24:1743–1751PubMedCrossRefGoogle Scholar
  56. 56.
    Papazian L, Albanèse J, Thirion X (1993) Effect of bolus doses of midazolam on intracranial pressure and cerebral perfusion pressure in patients with severe head injury. Br J Anaesth 71: 267–271PubMedCrossRefGoogle Scholar
  57. 57.
    Stewart L, Bullock R, Rafferty C (1994) Propofol sedation in severe head injury fails to control high IGP, but reduces brain metabolism. Acta Neurochir 60 (suppl): 544–550Google Scholar
  58. 58.
    Schwartz M, Tator C, Towed D (1984) The University of Toronto head injury treatment study: A prospective randomized comparison of pentobarbital and mannitol. Can J Neurol Sci 11: 434–440PubMedGoogle Scholar
  59. 59.
    Ward JD, Becker DP, Miller JD (1985) Failure of prophylactic barbiturate coma in the treatment of severe head injury. J Neurosurg 62:383–391PubMedCrossRefGoogle Scholar
  60. 60.
    Eisenberg HM, Frankowski RE, Contant CF, Marshall LF, Walker MD (1988) High-dose barbiturate control of elevated intracranial pressure in patients with severe head injury. J Neurosurg 69:15–23PubMedCrossRefGoogle Scholar
  61. 61.
    Albanèse J, Arnaud S, Rey M (1997) Ketamine decreases intracranial pressure and electro-encephalogram activity in traumatic brain injury patients during propofol sedation. Anesthesiology 87:1328–1334PubMedCrossRefGoogle Scholar
  62. 62.
    Kolenda H, Gremmelt A, Rading S (1996) Ketamine for analgosedative therapy in intensive care treatment of head-injured patients. Acta Neurochir 138:1193–1199CrossRefGoogle Scholar
  63. 63.
    Sperry RJ, Bailey PL, Reichman MV (1992) Fentanyl and sufentanil increase pressure in head trauma patients. Anesthesiology 77:416–420PubMedCrossRefGoogle Scholar
  64. 64.
    Werner C, Kochs E, Bause H (1995) Effects of sufentanil on cerebral hemodynamics and intracranial pressure in patients with brain injury. Anesthesiology 83:721–727PubMedCrossRefGoogle Scholar
  65. 65.
    Albanèse J, Durbec O, Viviand X (1993) Sufentanil increases intracranial pressure in patients with head trauma. Anesthesiology 79:793–800CrossRefGoogle Scholar
  66. 66.
    Albanèse J, Viviand X, Potié F (1999) Sufentanil, fentanyl and alfentanil in head trauma patients: a study on cerebral hemodynamics. Crit Care Med 27:407–411PubMedCrossRefGoogle Scholar
  67. 67.
    Albanèse J, Viviand X, Vialet R (1995) Quel morphinique pour la sédation prolongée? Réan Urg 4:11s–17sCrossRefGoogle Scholar
  68. 68.
    Fahy BG, Matjasko J (1994) Disadvantages of prolonged neuromuscular blockade in patients with head injury. J Neurosurg Anesthesiol 6:136–144PubMedGoogle Scholar
  69. 69.
    Wilson JA, Brunch CL (1994) Neuromuscular blockade in head-injured patients with increased intracranial pressure: continuous versus intermittent use. J Neurosurg Anesthesiol 2:139–141Google Scholar
  70. 70.
    Khuenl-Brady KS, Reitstätter B, Schlager A, et al (1994) Long-term administration of pancuronium and pipecuronium in the intensive care unit. Anesth Analg 78:1082–1088PubMedCrossRefGoogle Scholar
  71. 71.
    Kovarik WP, Mayberg TS, Lam AM, et al (1994) Succinylcholine does not change intracranial pressure, cerebral blood flow velocity, or the electroencephalogram in patients with neurologic injury. Anesth Analg 78:469–473PubMedCrossRefGoogle Scholar
  72. 72.
    Hsiang JK, Chesnut RM, Crisp CB, et al (1994) Early, routine paralysis for intracranial pressure control in severe head injury: is it necessary? Crit Care Med 22:1471–1476PubMedCrossRefGoogle Scholar
  73. 73.
    Brain Trauma Foundation (1996) Antiseizure prophylaxis following head injury. J Neurotrauma 13:731–735CrossRefGoogle Scholar
  74. 74.
    Brain Trauma Foundation (1996) Critical pathway for the treatment of established intracranial hypertension. J Neurotrauma 13:719–720CrossRefGoogle Scholar
  75. 75.
    Brain Trauma Foundation (1996) The use of mannitol in severe head injury. J Neurotrauma 13: 705–714CrossRefGoogle Scholar
  76. 76.
    Donato T, Shapira Y, Artra A, et al (1994) Effect of mannitol on cerebrospinal fluid dynamics and brain tissue edema. Anesth Analg 78:58–66PubMedCrossRefGoogle Scholar
  77. 77.
    Zornow MH, Prough DS (1995) Fluid management in patient with traumatic brain injury. New Horiz 3:488–498PubMedGoogle Scholar
  78. 78.
    Marion DW, Penrod LE, Kelsey SF, et al (1996) Treatment of traumatic brain injury with moderate hypothermia. N Engl J Med 336:540–546CrossRefGoogle Scholar
  79. 79.
    Asgeirsson B, Grände PO, Nordstrom CH (1994) A new therapy of post-trauma brain oedema based on haemodynamic principles for brain volume regulation. Intensive Care Med 20: 260–267PubMedCrossRefGoogle Scholar
  80. 80.
    Hills MW, Deane SA (1993) Head injury and facial injury: is there an increased risk of cervical spine injury? J Trauma 34:549–554PubMedCrossRefGoogle Scholar
  81. 81.
    Woodring JH, Lee C (1993) Limitations of cervical radiography in the evaluation of acute cervical trauma. J Trauma 34:32–39PubMedCrossRefGoogle Scholar
  82. 82.
    Davis JW, Phreaner DL, Hoyt DB, Mackersie RC (1993) The etiology of missed cervical spine injuries. J Trauma 34:342–346PubMedCrossRefGoogle Scholar
  83. 83.
    Wisner DH, Victor NS, Holcroft JW (1993) Priorities in the management of multiple trauma: intracranial versus intra-abdominal injury. J Trauma 35:271–276PubMedCrossRefGoogle Scholar
  84. 84.
    Thomason M, Messick J, Rutledge R, et al (1993) Head CT scanning versus urgent exploration in the hypotensive blunt trauma patient. J Trauma 34:40–45PubMedCrossRefGoogle Scholar
  85. 85.
    Winchell RJ, Hyt DB, Simons RK (1995) Use of computed tomography of the head in the hypotensive blunt-trauma patient. Ann Emerg Med 25:737–742PubMedCrossRefGoogle Scholar
  86. 86.
    Huang MS, Shih HC, Wu JK, et al (1995) Urgent laparotomy versus emergency craniotomy for multiple trauma with head injury patients. J Trauma 38:154–157PubMedCrossRefGoogle Scholar
  87. 87.
    Edouard A, Minoz O (1997) Aspects hémodynamiques des polytraumatisés. In: SFAR (ed) Conférences d’actualisation. 39e Congrès National d’anesthésie et de réanimation. Elsevier, Paris, pp 445–463Google Scholar
  88. 88.
    Portier F, Marciano S, Thomachot L, Boisson C, Martin C, Panuel M (1997) Topogrammes radio-logiques numérisés systématiques du rachis cervical des polytraumatisés et des traumatisés crâniens réahsés sur la table de scanner. Réan Urg 6:709 (Abst)CrossRefGoogle Scholar
  89. 89.
    Martin C, Domergue R, et le Groupe d’experts en médecine d’urgence du sud-est (1997) Prise en charge préhospitalière et hospitahère précoce d’un état de choc hémorragique d’origine trau-matique. Ann Fr Anesth Réanim 16:1030–1036PubMedCrossRefGoogle Scholar
  90. 90.
    Portier F, Chaumoitre K, Albanèse J, Arnaud S, Martin C, Panuel M (1997) Scanner corps entier systématique dans la prise en charge radiologique du polytraumatisé. Réan Urg 6:709 (Abst)CrossRefGoogle Scholar
  91. 91.
    Shackford SR, Nald SL, Ross SE, et al (1992) The clinical utility of computed tomographic scanning and neurologic examination in the management of patients with minor head injuries. J Trauma 33:385–394PubMedCrossRefGoogle Scholar
  92. 92.
    Servadei F, Nanni A, Nasi MT, et al (1995) Evolving brain lesions in the first 12 hours after head injury: analysis of 37 comatose patients. Neurosurgery 37:899–906PubMedCrossRefGoogle Scholar
  93. 93.
    Schmeling GJ, Schwab JP (1995) Polytrauma care: the effect of head injuries and timing of skeletal fixation. Clin Orthop 318:106–116PubMedGoogle Scholar
  94. 94.
    Poole GV, Miller JD, Agnew SG, Griswold JA (1992) Lower extremity fracture fixation in head-in-jury patients. J Trauma 32:654–659PubMedCrossRefGoogle Scholar
  95. 95.
    Jaicks RR, Cohn SM, Moller BA (1997) Early fracture fixation may be deleterious after head injury. J Trauma 42:1–5PubMedCrossRefGoogle Scholar
  96. 96.
    Feldman Z, Kanter MJ, Robertson CS, et al (1992) Effect of head elevation on intracranial pressure, cerebral perfusion pressure, and blood flow in head injured patients. J Neurosurg 76: 207–211PubMedCrossRefGoogle Scholar
  97. 97.
    Cruz J (1998) The first decade of continuous monitoring of jugular bulb oxyhemoglobin saturation: management strategies and clinical outcome. Crit Care Med 26:344–351PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • J. Albanèse
  • M. Léone
  • C. Martin

There are no affiliations available

Personalised recommendations