Abstract
We evaluate a CAD device with detection and classification capabilities and compare conventional to computerized analysis. 243 cases (126 malignant, 117 benign) were analysed using BI-RADS and digitized (600 DPI, 12 bits). Lesions were detected, classified by likelihood of malignancy, and stratified into BI-RADS categories 2–5 by the CAD device. The falsely detected findings scored by CAD as low probability of malignancy were discarded to evaluate the true false positive rate. The CAD device sensitivity was 96% for masses and 95% for clusters of MCs. Malignancies were correctly classified by CAD in 95%. 67% of the false positive detected masses and 76% of the false positive clusters were classified benign by the CAD device, reducing the false positive rate per view from 0.59 to 0.20 for masses and from 0.30 to 0.07 for clusters. Conventional interpretation yielded a ROC Az of 0.76. CAD improved the Az to 0.88 (pO.OOl).
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References
Breast imaging reporting and data system American College of Radiology, Reston Virginia(1993).
Liberman L, Abramson AF, Squires FB, et al. The breast imaging reporting and data system: Positive predictive value of mammographic features and final assessment categories. Am. J. Roentgenol. 1998 171: 35–40.
Huo Z, Giger M.L, Vybrony CJ, Wolverton DE, Schmidt RA, Doi K. Automated computerized classification of malignant and benign masses on digitized mammograms. Acad. Radiol. 1998; 5: 155–168.
Fields S, Leichter I, Bamberger P, et al. Clinical evaluation of computerized enhancement and analysis of mammographic findings. In: Doi K, Giger ML, Nishikawa RM, Schmidt RA (eds.) Digital mammography ’96. Amsterdam, Holland: Elsevier, 1996; pp 81–86.
Leichter I., Bamberger P., Novak B., Fields S., Buchbinder S., Lederman R. Quantitative Characterization of Mass Lesions on Digitized Mammograms for Computer Assisted Diagnosis. Investigative Radiology 2000; 35: 366–372.
Leichter I, Lederman R, Bamberger P, et al. The use of an interactive software program for quantitative characterization of microcalcifications on digitized film-screen mammograms. Invest. Radiol. 1999 34: 394–400.
Efron B. The jackknife, the bootstrap and other resampling plans. Philadelphia PA: Society for Industrial and applied Mathematics (SIAM), 1982.
Metz CE. ROC methodology in radiologic imaging. Invest. Radiol. 1986; 21: 720–732.
Hanley JA, McNeil BJ. A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology 1983; 148: 839–843.
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© 2003 Springer-Verlag Berlin Heidelberg
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Fields, S. et al. (2003). Improved mammographic accuracy with CAD assisted classification of lesions. In: Peitgen, HO. (eds) Digital Mammography. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59327-7_69
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DOI: https://doi.org/10.1007/978-3-642-59327-7_69
Publisher Name: Springer, Berlin, Heidelberg
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