Skip to main content

Improved mammographic accuracy with CAD assisted classification of lesions

  • Conference paper
Digital Mammography

Abstract

We evaluate a CAD device with detection and classification capabilities and compare conventional to computerized analysis. 243 cases (126 malignant, 117 benign) were analysed using BI-RADS and digitized (600 DPI, 12 bits). Lesions were detected, classified by likelihood of malignancy, and stratified into BI-RADS categories 2–5 by the CAD device. The falsely detected findings scored by CAD as low probability of malignancy were discarded to evaluate the true false positive rate. The CAD device sensitivity was 96% for masses and 95% for clusters of MCs. Malignancies were correctly classified by CAD in 95%. 67% of the false positive detected masses and 76% of the false positive clusters were classified benign by the CAD device, reducing the false positive rate per view from 0.59 to 0.20 for masses and from 0.30 to 0.07 for clusters. Conventional interpretation yielded a ROC Az of 0.76. CAD improved the Az to 0.88 (pO.OOl).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Breast imaging reporting and data system American College of Radiology, Reston Virginia(1993).

    Google Scholar 

  2. Liberman L, Abramson AF, Squires FB, et al. The breast imaging reporting and data system: Positive predictive value of mammographic features and final assessment categories. Am. J. Roentgenol. 1998 171: 35–40.

    CAS  Google Scholar 

  3. Huo Z, Giger M.L, Vybrony CJ, Wolverton DE, Schmidt RA, Doi K. Automated computerized classification of malignant and benign masses on digitized mammograms. Acad. Radiol. 1998; 5: 155–168.

    Article  PubMed  CAS  Google Scholar 

  4. Fields S, Leichter I, Bamberger P, et al. Clinical evaluation of computerized enhancement and analysis of mammographic findings. In: Doi K, Giger ML, Nishikawa RM, Schmidt RA (eds.) Digital mammography ’96. Amsterdam, Holland: Elsevier, 1996; pp 81–86.

    Google Scholar 

  5. Leichter I., Bamberger P., Novak B., Fields S., Buchbinder S., Lederman R. Quantitative Characterization of Mass Lesions on Digitized Mammograms for Computer Assisted Diagnosis. Investigative Radiology 2000; 35: 366–372.

    Article  PubMed  CAS  Google Scholar 

  6. Leichter I, Lederman R, Bamberger P, et al. The use of an interactive software program for quantitative characterization of microcalcifications on digitized film-screen mammograms. Invest. Radiol. 1999 34: 394–400.

    Article  PubMed  CAS  Google Scholar 

  7. Efron B. The jackknife, the bootstrap and other resampling plans. Philadelphia PA: Society for Industrial and applied Mathematics (SIAM), 1982.

    Google Scholar 

  8. Metz CE. ROC methodology in radiologic imaging. Invest. Radiol. 1986; 21: 720–732.

    Article  PubMed  CAS  Google Scholar 

  9. Hanley JA, McNeil BJ. A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology 1983; 148: 839–843.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Fields, S. et al. (2003). Improved mammographic accuracy with CAD assisted classification of lesions. In: Peitgen, HO. (eds) Digital Mammography. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59327-7_69

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-59327-7_69

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63936-4

  • Online ISBN: 978-3-642-59327-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics