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Die Aktivierung des Transkriptionsfaktors NF-KB und des Protoonkogens c-fos in humanen Fibroblasten nach zyklischer mechanischer Dehnung

  • M. van Griensven
  • J. Zeichen
  • M. Skutek
  • U. Bosch

Zusammenfassung

Mit den Erkenntnissen zur Pathophysiologie der Gelenkimmobilisation hat die Rehabilitation von Sehnen-und Bandverletzungen in den letzten Jahren einen entscheidenden Wandel erfahren. Die Binde-und Stützgewebe des Bewegungsapparates, zu deren Hauptaufgabe der Widerstand gegenüber mechanischer Belastung zählt, werden maßgeblich durch physikalische Faktoren beeinflusst. Langfristig immobilisierende Maßnahmen mit Inaktivitätsosteoporose, Muskelatrophie, Kapselkontrakturen, Adhäsionen von Gleitschichten und Degeneration des Gelenkknorpels wurden zugunsten frühfunktioneller Methoden verlassen. Die biomechanischen Eigenschaften von Sehnen, Ligamenten sowie von Bandrekonstruktionen werden durch eine funktionelle Behandlung positiv beeinflusst [30,31].

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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • M. van Griensven
  • J. Zeichen
  • M. Skutek
  • U. Bosch

There are no affiliations available

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