Pharmacological Thrombolysis - Systematic Therapy

  • M. Martin
Part of the Medical Radiology book series (MEDRAD)

Abstract

The development of chronic arterial occlusion is due to three processes: the first step is an arteriosclerotic lesion of the intima. Causes under discussion are: radiation (Nylander et al. 1978; Silverberg et al. 1978), carbon monoxide (Marshall et al. 1978), high blood pressure (Wooshmann and Nitschkoff 1966), lipid infiltration (Doerr 1963; Kannel et al. 1979), and old age (Schoop and Schmidtke 1973).

Keywords

Fibrinolytic Therapy Aortic Occlusion Arteriosclerotic Lesion Fibrinolytic Treatment Pharmacological Thrombolysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Alexander K, Buhl U, Holsten D, Poliwoda H, Wagner HH (1968) Fibrinolytische Therapie des chronischen Arterienverschlusses. Med Klin 63:2067-2070PubMedGoogle Scholar
  2. Deutsch E, Ehringer H (1972) Thrombolytic therapy in chronic arterial occlusions. J Clin Pathol 25:644–645PubMedCrossRefGoogle Scholar
  3. Doerr W (1963) Perfusionstherorie der Arteriosklerose. Thieme, StuttgartGoogle Scholar
  4. Dotter CHT, Rosch J, Seaman AJ, Dennis D, Massey WH (1972) Streptokinase treatment of thromboembolic disease. Radiology 102:283–290PubMedGoogle Scholar
  5. Ehringer H, Fischer M (1968) Erfolgreiche thrombolytische Therapie bei subakuten arteriellen Thrombosen. Med Welt:1726–1730Google Scholar
  6. Harker LA, Ross R, Slichter SJ (1975) Chronic endothelial cell injury and platelet-factor induced arteriosclerosis (Abstr). Vth Congress of the International Society on Thrombosis and Haemostasis, July 21–26, Paris, p 56Google Scholar
  7. Heinrich F (1975) Streptokinase-Therapie bei chronischer arterieller Verschlußkrankheit. Ergebnisse einer multizentrischen Studie. Medizinische Verlagsgesellschaft MarburgGoogle Scholar
  8. Heinrich F, Heinrich U (1996) Ergebnis der Nordbadischen Venen-Lyse-NBVL-Studie. Prospektive phlebographisch kontrollierte randomisierte multizentrische Prüfung der Wirkung von ultrahoher versus konventionell dosierter Streptokinase bei frischen Thromben in tiefen Bein-Becken-Venen. Med Klin 91:1–13Google Scholar
  9. Heinrich F, Schmutzler R (1972) Ergebnisse der Thrombolysebehandlung chronischer Glied- maßenarterienverschlüsse. Dtsch Med J 23:351–358PubMedGoogle Scholar
  10. Kaindl F, Pilgerstorfer HW, Weidinger P, Fischer M (1968) Untersuchungen zur Thrombolyse älterer arterieller Verschlüsse mit Streptokinase. Med Welt: 1731–1733Google Scholar
  11. Kannel WB, Castelli WP, Gordon T (1979) Cholesterol in the prediction of atherosclerotic disease. Ann Intern Med 90:85–95PubMedCrossRefGoogle Scholar
  12. Le Veen HH, Diaz CA (1972) Venous and arterial occlusive disease treated by enzymatic clot lysis. Arch Surg 105:927–936CrossRefGoogle Scholar
  13. Marshall M, Hess H, Staubesand J (1978) Experimentelle Untersuchungen über den Risikofaktor Rauchen. VASA 7:389–397PubMedGoogle Scholar
  14. Martin M (1982) Streptokinase in chronic arterial disease. CRC Press, Boca RatonGoogle Scholar
  15. Martin M, Fiebach BJO (1994) Fibrinolytische Behandlung peripherer Arterien- und Venenverschlüsse. Huber, BernGoogle Scholar
  16. Martin M, Schoop W, Zeitler E (1970) Thrombolyse bei chronischer Arteriopathie. Huber, BernGoogle Scholar
  17. Nylander G, Pettersson F, Swedenborg J (1978) Localized arterial occlusions in patients treated with pelvic field radiation for cancer. Cancer 41:2158–216PubMedCrossRefGoogle Scholar
  18. Persson AV, Thomson JE, Patmann D (1973) Streptokinase as an adjunct to arterial surgery. Arch Surg 107:779–784PubMedCrossRefGoogle Scholar
  19. Robbins SL, Angell M (1976) Basic pathology. Saunders, PhiladelphiaGoogle Scholar
  20. Schoop W, Schmidtke I (1973) Spontane Lumenerweiterungen von Arterienstenosen. Herz Kreisl 5:9Google Scholar
  21. Schoop W, Martin M, Zeitler E (1968a) Beseitigung alter Arterienverschlüsse durch intravenöse Streptokinaseinfusion. Dtsch Med Wochenschr 93:2312–2324Google Scholar
  22. Schoop W, Martin M, Zeitler E (1968b) Beseitigung von Stenosen in Extremitätenarterien durch intravenöse Streptokinase -Therapie. Dtsch Med Wochenschr 93:1629–1633PubMedCrossRefGoogle Scholar
  23. Silverberg GD, Britt RH, Don Goffinet R (1978) Radiation-induced carotid artery disease. Cancer 41:130–137PubMedCrossRefGoogle Scholar
  24. Verstraete M, Vermylen J, Donati MB (1971) The effect of streptokinase on chronic arterial occlusions and stenoses. Ann Intern Med 74:377–382PubMedCrossRefGoogle Scholar
  25. Wooshmann H, Nitschkoff ST (1966) Histochemische Untersuchungen an Aortenläsionen nach experimenteller Hypertonie. Acta Biol Med Ger 16:70–78Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • M. Martin
    • 1
  1. 1.Angiologische Praxis, Klinikum DuisburgDuisburgGermany

Personalised recommendations