Reactionary and Reparative Dentin-Like Structures

  • Michel GoldbergEmail author


Reactionary dentin-like is produced by odontoblasts and Hoehl’s cell after a carious decay, beneath a calciotraumatic line. Five SIBLINGs have been identified, together with the metalloproteinase-2 (MMP-2), whereas SMAD-2 and SMAD-4 are implicated in the synthesis of collagen. Reparative dentin is similar to a bone-like (osteodentin) structure and produced by pulp cells. BMPs, OP-1 or BMP-7, and other growth factors have also been identified in the reparative dentin. A series of SIBLINGs, fibronectin, ameloblastin, MMP-3, and MMP-9 are implicated in the formation of reparative dentin allowing the closure of a pulp exposure.


Dental Pulp Pulp Cell Pulp Chamber Dental Pulp Cell Dental Pulp Stem Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of Oral Biology, Institut National de la Santé et de la Recherche MédicaleUniversité Paris DescartesParisFrance

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