TRPs: Truly Remarkable Proteins
The family of transient receptor potential cation channels has received in the last 10 years a tremendous interest because members of this family are involved in a plethora of cell functions and have been identified as causal for many hereditary and acquired diseases. We shortly introduce these channels, summarize nomenclature and chromosomal location of the 28 mammalian Trp genes, and list the available Trp-deficient mouse lines.
KeywordsTRP cation channel proteins TRP phylogenetic tree Trp gene Chromosomal location Trp gene knockout Trp-deficient mouse strain Mouse (animal) model
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