The scid Mouse Mutant

  • M. Bosma
  • W. Schuler
  • G. Bosma
Conference paper
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 137)

Abstract

The scid mutation occurred in the C.B-17Icr (C.B-17) inbred strain, an immunoglobulin heavy chain (Igh) congenic partner strain of BALB/cAnlcr (BALB/c) . The C.B-17 strain was derived from the 13th backcross generation of the original C.B stock of M. Potter. C.B-17 mice are not known to differ from BALB/c mice except that a portion of their chromosome 12 comes from the C57BL/Ka strain and includes the C57BL/Ka Igh locus and other closely-linked genes.

Keywords

Scid Mouse Severe Combine Immunodeficiency Severe Combine Immune Deficiency Antigen Receptor Gene Abelson Murine Leukemia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1988

Authors and Affiliations

  • M. Bosma
    • 1
  • W. Schuler
    • 1
  • G. Bosma
    • 1
  1. 1.Institute for Cancer ResearchFox Chase Cancer CenterPhiladelphiaUSA

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