Optimised Three-Dimensional Treatment Planning for Volumes with Concave Outlines, Using a Multileaf Collimator

Abstract

The aim of curative radiotherapy is to deliver a high dose, as uniformly as possible, to a target volume (TV) which encompasses the tumour, any marginal spread of disease and perhaps a border of safety, whilst minimising the dose to radiosensitive structures lying nearby. The widespread availability of tomographic medical images including X-ray computed tomography and magnetic resonance tomography enables sensitive volumes (SV) and TV to be accurately determined in three-dimensions (e.g. Fraass et al. 1991). The goal of conformal radiotherapy is to tailor the treatment fields so that the differential between the high-dose TV and the low-dose SV is as wide as possible. Under these circumstances dose escalation may be appropriate, thus increasing the probability of local control. A recent review of conformal therapy sets out the issues (Tait and Nahum 1990).

Keywords

Target Volume Dose Distribution Conformal Radiotherapy Sensitive Volume Uniform Weight 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • S. Webb
    • 1
  1. 1.Joint Department of PhysicsInstitute of Cancer Research and Royal Marsden HospitalSutton, SurreyUK

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