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Automated Embryo Stage Classification in Time-Lapse Microscopy Video of Early Human Embryo Development

  • Yu Wang
  • Farshid Moussavi
  • Peter Lorenzen
Part of the Lecture Notes in Computer Science book series (LNCS, volume 8150)

Abstract

The accurate and automated measuring of durations of certain human embryo stages is important to assess embryo viability and predict its clinical outcomes in in vitro fertilization (IVF). In this work, we present a multi-level embryo stage classification method to identify the number of cells at every time point of a time-lapse microscopy video of early human embryo development. The proposed method employs a rich set of hand-crafted and automatically learned embryo features for classification and avoids explicit segmentation or tracking of individual embryo cells. It was quantitatively evaluated using a total of 389 human embryo videos, resulting in a 87.92% overall embryo stage classification accuracy.

Keywords

embryo stage classification adaboost bag of features 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Yu Wang
    • 1
  • Farshid Moussavi
    • 1
  • Peter Lorenzen
    • 1
  1. 1.Auxogyn, Inc.Menlo ParkUSA

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