Cancer Stem Cell Modeling Using a Cellular Automaton

  • Ángel Monteagudo
  • José Santos Reyes
Part of the Lecture Notes in Computer Science book series (LNCS, volume 7931)

Abstract

We used a cellular automaton model for cancer growth simulation at cellular level, based on the presence of different cancer hallmarks acquired by the cells. The rules of the cellular automaton determine cell mitotic and apoptotic behaviors, which are based on the acquisition of the hallmarks in the cells by means of mutations. The simulation tool allows the study of the emergent behavior of tumor growth. This work focuses on the simulation of the behavior of cancer stem cells to inspect their capability of regeneration of tumor growth in different scenarios.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Ángel Monteagudo
    • 1
  • José Santos Reyes
    • 1
  1. 1.Computer Science DepartmentUniversity of A CoruñaSpain

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