Abstract
Sebaceous gland carcinoma (SGC) is a malignant neoplasm capable of aggressive local behavior and metastasis to regional lymph nodes and distant organs. It originates from cells of the sebaceous glands and occurs most often in the periorbital area, usually in the eyelid [1]. This lesion is considered among the most lethal of all ocular adnexal tumors [2].
Keywords
Basal Cell Carcinoma Merkel Cell Carcinoma Epithelial Membrane Antigen Meibomian Gland Sebaceous Carcinoma
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References
- 1.Shields JA, Demirci H, Marr BP, et al. Sebaceous carcinoma of the ocular region: a review. Surv Ophthalmol. 2005;50:103–22.PubMedCrossRefGoogle Scholar
- 2.Kass LG, Hornblass A. Sebaceous carcinoma of the ocular adnexa. Surv Ophthalmol. 1989;33:477–90.PubMedCrossRefGoogle Scholar
- 3.Margo CE, Mulla ZD. Malignant tumors of the eyelid: a population-based study of non-basal cell and non-squamous cell malignant neoplasms. Arch Ophthalmol. 1998;116:195–8.PubMedCrossRefGoogle Scholar
- 4.Khan JA, Doane JF, Grove AS. Sebaceous and meibomian carcinomas of the eyelid. Recognition, diagnosis, and management. Ophthal Plast Reconstr Surg. 1991;7:61–6.PubMedCrossRefGoogle Scholar
- 5.Rao NA, Hiadayat AA, McLean IW, et al. Sebaceous carcinomas of the ocular adnexa: A clinicopathologic study of 104 cases, with five–year follow-up data. Hum Pathol. 1982;13:113–22.PubMedCrossRefGoogle Scholar
- 6.Dasgupta T, Wilson LD, Yu JB. A retrospective review of 1349 cases of sebaceous carcinoma. Cancer. 2009;115:158–65.PubMedCrossRefGoogle Scholar
- 7.Shields JA, Demirci H, Marr BP, Eagle Jr RC, Shields CL. Sebaceous carcinoma of the eyelids. Personal experience with 60 Cases. Ophthalmology. 2004;111:2151–7.PubMedCrossRefGoogle Scholar
- 8.Wick MR, Goellner JR, Wolfe JT, et al. Adnexal carcinomas of the skin. II. Extraocular sebaceous carcinomas. Cancer. 1985;56:1163–72.PubMedCrossRefGoogle Scholar
- 9.Shields CL, Shields JA, White D, et al. Types and frequency of lesions of the caruncle. Am J Ophthalmol. 1986;102:771–8.PubMedGoogle Scholar
- 10.von Below H, Rose GE, McCartney AC, et al. Multicentric sebaceous gland carcinoma of the lid? Br J Ophthalmol. 1993;77:819–20.CrossRefGoogle Scholar
- 11.Shields JA, Shields CL. Sebaceous carcinoma of the glands of Zeis. Ophthal Plast Reconstr Surg. 1988;4:11–4.PubMedCrossRefGoogle Scholar
- 12.Cavanagh HD, Green WR, Goldberg HK. Multicentric sebaceous adenocarcinoma of the meibomian gland. Am J Ophthalmol. 1974;77:326–32.PubMedGoogle Scholar
- 13.Herman DC, Chan CC, Bartley GB, et al. Immunohistochemical staining of sebaceous cell carcinoma of the eyelid. Am J Ophthalmol. 1989;107:127–32.PubMedGoogle Scholar
- 14.Sinard JH. Immunohistochemical distinction of ocular sebaceous carcinoma from basal cell and squamous cell carcinoma. Arch Ophthalmol. 1999;117:776–83.PubMedCrossRefGoogle Scholar
- 15.Asadi-Amoli F, Khoshnevis F, Haeri H, Jahanzad I, Pazira R, Shahsiah R. Comparative Examination of androgen receptor reactivity for differential diagnosis of sebaceous carcinoma from squamous cell and basal cell carcinoma. Am J Clin Pathol. 2010;134:22–6.PubMedCrossRefGoogle Scholar
- 16.Arathi CA, Vijaya C. Scrape cytology in the early diagnosis of eyelid sebaceous carcinoma. J Cytol. 2010;27:140–2.PubMedCrossRefGoogle Scholar
- 17.Gill M, Garg S, Kalra R, Sen R. Sebaceous carcinoma of the eyelid diagnosed on fine needle aspiration cytology. J Cytol. 2012;29:75–6.PubMedCrossRefGoogle Scholar
- 18.Kwitko ML, Boniuk M, Zimmerman LE. Eyelid tumors with reference to lesions confused with squamous cell carcinoma: incidence and errors in diagnosis. Arch Ophthalmol. 1963;69:696–7.CrossRefGoogle Scholar
- 19.Lai TF, Huilgol SC, Selva D, et al. Eyelid sebaceous carcinoma masquerading as in situ squamous cell carcinoma. Dermatol Surg. 2004;30:222–5.PubMedCrossRefGoogle Scholar
- 20.Cook Jr BE, Bartley GB. Treatment options and future prospects for the management of eyelid malignancies: an evidence-based update. Ophthalmology. 2001;108:2088–98.PubMedCrossRefGoogle Scholar
- 21.Folberg R, Whitaker DC, Tse DT, et al. Recurrent and residual sebaceous carcinoma after Mohs’ excision of the primary lesion. Am J Ophthalmol. 1987;103:817–23.PubMedGoogle Scholar
- 22.Spencer JM, Nossa R, Tse DT, et al. Sebaceous carcinoma of the eyelid treated with Mohs micrographic surgery. J Am Acad Dermatol. 2001;44:1004–9.PubMedCrossRefGoogle Scholar
- 23.Shields CL, Naseripour M, Shields JA, et al. Topical mitomycin-C for pagetoid invasion of the conjunctiva by eyelid sebaceous gland carcinoma. Ophthalmology. 2002;109:2129–33.PubMedCrossRefGoogle Scholar
- 24.Rosner M, Hadar I, Rosen N. Successful treatment with mitomycin C eye drops for conjunctival diffuse intraepithelial neoplasia with sebaceous features. Ophthal Plast Reconstr Surg. 2003;19:477–9.PubMedCrossRefGoogle Scholar
- 25.Tumuluri K, Kourt G, Martin P. Mitomycin C in sebaceous gland carcinoma with pagetoid spread. Br J Ophthalmol. 2004;88:718–9.PubMedCrossRefGoogle Scholar
- 26.Yen MT, Tse DT, Wu X, et al. Radiation therapy for local control of eyelid sebaceous cell carcinoma: report of two cases and review of the literature. Ophthal Plast Reconstr Surg. 2000;16:211–5.PubMedCrossRefGoogle Scholar
- 27.Nijhawan N, Ross MI, Diba R, et al. Experience with sentinel lymph node biopsy for eyelid and conjunctival malignancies at cancer center. Ophthal Plast Reconstr Surg. 2004;20:291–5.PubMedCrossRefGoogle Scholar
- 28.Tryggvason G, Bayon R. MD, Pagedar NA. Epidemiology of sebaceous carcinoma of the head and neck: Implications for lymph node management. Head Neck. 2012;34:1765–8.PubMedCrossRefGoogle Scholar
- 29.Esmaeli B, Nasser QJ, Cruz H, Fellman M, Warneke CL, Ivan D. American Joint Committee on Cancer T Category for eyelid sebaceous carcinoma correlates with nodal metastasis and survival. Ophthalmology. 2012;119:1078–82.PubMedCrossRefGoogle Scholar
- 30.Murthy R, Honavar SG, Burman S, et al. Neoadjuvant chemotherapy in the management of sebaceous gland carcinoma of the eyelid with regional lymph node metastasis. Ophthal Plast Reconstr Surg. 2005;21:307–9.PubMedCrossRefGoogle Scholar
- 31.Hata M, Koike I, Omura M, Maegawa J, Ogino I, Inoue T. Noninvasive and curative radiation therapy for sebaceous carcinoma of the eyelid. Int J Radiat Oncol Biol Phys. 2012;82:605–11.PubMedCrossRefGoogle Scholar
- 32.Deo SVS, Shukla NK, Singh M, Jha D, Khanna P, Kallianpur A. Locally Advanced Sebaceous Cell Carcinoma (T3) of Eyelid: Incidence and pattern of nodal metastases and combined modality management approach. Orbit. 2012;31:150–4.PubMedCrossRefGoogle Scholar
- 33.Kiyosaki K, Nakada C, Hijiya N, Tsukamoto Y, Matsuura K, Nakatsuka K, Daa T, Yokoyama S, Imaizumi M, Moriyama M. Analysis of p53 mutations and the expression of p53 and p21WAF1/CIP1 protein in 15 cases of sebaceous carcinoma of the eyelid. Invest Ophthalmol Vis Sci. 2010;51:7–11.PubMedCrossRefGoogle Scholar
- 34.Edge SE. Carcinoma of the eyelid. In: Edge SE, Byrd DR, Carducci MA, Compton CA, editors. AJCC Cancer Staging Manual. 7th ed. New York: Springer; 2010.Google Scholar
- 35.Callahan EF, Appert DL, Roenigk RK, Bartley GB. Sebaceous carcinoma of the eyelid: a review of 14 cases. Dermatol Surg. 2004;30:1164–8.PubMedCrossRefGoogle Scholar
- 36.Boniuk M, Zimmerman LE. Sebaceous carcinoma of the eyelid, eyebrow, caruncle, and orbit. Trans Am Acad Ophthalmol Otolaryngol. 1968;72:619–41.PubMedGoogle Scholar
- 37.Muqit MM, Roberts F, Lee WR, Kemp E. Improved survival rates in sebaceous carcinoma of the eyelid. Eye. 2004;18:49–53.PubMedCrossRefGoogle Scholar
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