Seltene hormonaktive Tumoren des Pankreas – chirurgische Therapie

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Zusammenfassung

Hormonaktive neuroendokrine Neoplasien des Pankreas umfassen neben Insulinomen und Gastrinomen sogenannte „seltene hormonaktive Tumoren“, welche sehr unterschiedliche Hormone sezernieren können. Die Therapie dieser überwiegend malignen Tumoren erfolgt entsprechend der durch die European Neuroendocrine Tumor Society (ENETS) und die North American Neuroendocrine Tumor Society (NANETS) formulierten Leitlinien. Die operative Therapie stellt hierbei einen zentralen Bestandteil der Therapiestrategien dar, welche einen kurativen oder palliativen Ansatz verfolgen können. Die Indikation zur operativen Therapie und die Wahl des notwendigen Resektionsausmaßes erfordern detaillierte Kenntnisse zur klinischen Situation und optimalerweise zum prospektiven Wachstumsverhalten des Tumors. Beim perioperativen Management ist die häufig ausgeprägte hormonspezifische Symptomatik zur berücksichtigen.

Keywords

neuroendokrine Neoplasie Pankreas Chirurgie hormonaktiv VIPom Glucagonom 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Klinik für Viszeral-, Thorax- und GefäßchirurgieJohannes Gutenberg-Universität MainzMainzDeutschland

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