Locoregional Tumor Therapy pp 141-154 | Cite as
Radiofrequency Ablation for Treating Malignant Tumors to the Liver
Chapter
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Abstract
Radiofrequency (RF) ablation like most thermal ablation techniques was initially established for treating inoperable HCC. In the face of its technical success and ease of use, the indications for RF ablation were rapidly extended, and it is now established for treating a wide range of primary and secondary liver malignancies and its use has been described in virtually all major organs.
Keywords
Liver Metastasis Local Recurrence Rate Colorectal Liver Metastasis Thermal Ablation Percutaneous Ethanol Injection
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
References
- 1.Llovet JM, Di Bisceglie AM, Bruix J, Kramer BS, Lencioni R, Zhu AX, Sherman M, Schwartz M, Lotze M, Talwalkar J, Gores GJ. Design and endpoints of clinical trials in hepatocellular carcinoma. J Natl Cancer Inst. 2008;100:698–711.PubMedCrossRefGoogle Scholar
- 2.Cho YK, Kim JK, Kim MY, Rhim H, Han JK. Systematic review of randomized trials for hepatocellular carcinoma treated with percutaneous ablation therapies. Hepatology. 2009;49:453–9.PubMedCrossRefGoogle Scholar
- 3.Nakazawa T, Kokubu S, Shibuya A, Ono K, Watanabe M, Hidaka H, Tsuchihashi T, Saigenji K. Radiofrequency ablation of hepatocellular carcinoma: correlation between local tumor progression after ablation and ablative margin. AJR Am J Roentgenol. 2007;188:480–8.PubMedCrossRefGoogle Scholar
- 4.Chen M-S, Li J-Q, Zheng Y, Guo R-P, Liang H-H, Zhang Y-Q, Lin X-J, Lau WY. A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma. Ann Surg. 2006;243:321–8.PubMedCentralPubMedCrossRefGoogle Scholar
- 5.Lü M-D, Kuang M, Liang L-J, Xie X-Y, Peng B-G, Liu G-J, Li D-M, Lai J-M, Li S-Q. Surgical resection versus percutaneous thermal ablation for early-stage hepatocellular carcinoma: a randomized clinical trial. Zhonghua Yi Xue Za Zhi. 2006;86:801–5.PubMedGoogle Scholar
- 6.Huang J, Yan L, Cheng Z, Wu H, Du L, Wang J, Xu Y, Zeng Y. A randomized trial comparing radiofrequency ablation and surgical resection for HCC conforming to the Milan criteria. Ann Surg. 2010;252:903–12.PubMedCrossRefGoogle Scholar
- 7.Le Li J, Zhang X, Liu X, Li B, Jiao T, Kang T. Clinical outcomes of radiofrequency ablation and surgical resection for small hepatocellular carcinoma: a meta-analysis. J Gastroenterol Hepatol. 2012;27:51–8.PubMedCrossRefGoogle Scholar
- 8.Tiong L, Maddern GJ. Systematic review and meta-analysis of survival and disease recurrence after radiofrequency ablation for hepatocellular carcinoma. Br J Surg. 2011;98:1210–24.PubMedCrossRefGoogle Scholar
- 9.Cho CM, Tak W-Y, Kweon Y-O, Kim S-K, Choi Y-H, Hwang Y-J, Kim Y-I. The comparative results of radiofrequency ablation versus surgical resection for the treatment of hepatocellular carcinoma. Korean J Hepatol. 2005;11:59–71.PubMedGoogle Scholar
- 10.Hiraoka A, Horiike N, Yamashita Y, Koizumi Y, Doi K, Yamamoto Y, Hasebe A, Ichikawa S, Yano M, Miyamoto Y, Ninomiya T, Otomi Y, Kokame M, Iwamura T, Ishimaru Y, Sogabe I, Kashihara K, Nishiura S, Ootani H, Takamura K, Kawasaki H. Efficacy of radiofrequency ablation therapy compared to surgical resection in 164 patients in Japan with single hepatocellular carcinoma smaller than 3 cm, along with report of complications. Hepatogastroenterology. 2008;55:2171–4.PubMedGoogle Scholar
- 11.Kobayashi M, Ikeda K, Kawamura Y, Yatsuji H, Hosaka T, Sezaki H, Akuta N, Suzuki F, Suzuki Y, Saitoh S, Arase Y, Kumada H. High serum des-gamma-carboxy prothrombin level predicts poor prognosis after radiofrequency ablation of hepatocellular carcinoma. Cancer. 2009;115:571–80.PubMedCrossRefGoogle Scholar
- 12.Takahashi S, Kudo M, Chung H, Inoue T, Nagashima M, Kitai S, Tatsumi C, Minami Y, Ueshima K, Fukunaga T, Haji S. Outcomes of nontransplant potentially curative therapy for early-stage hepatocellular carcinoma in Child-Pugh stage A cirrhosis is comparable with liver transplantation. Dig Dis. 2007;25:303–9.PubMedCrossRefGoogle Scholar
- 13.Santambrogio R, Opocher E, Zuin M, Selmi C, Bertolini E, Costa M, Conti M, Montorsi M. Surgical resection versus laparoscopic radiofrequency ablation in patients with hepatocellular carcinoma and Child-Pugh class a liver cirrhosis. Ann Surg Oncol. 2009;16:3289–98.PubMedCrossRefGoogle Scholar
- 14.Ueno S, Sakoda M, Kubo F, Hiwatashi K, Tateno T, Baba Y, Hasegawa S, Tsubouchi H. Surgical resection versus radiofrequency ablation for small hepatocellular carcinomas within the Milan criteria. J Hepatobiliary Pancreat Surg. 2009;16:359–66.PubMedCrossRefGoogle Scholar
- 15.Lupo L, Panzera P, Giannelli G, Memeo M, Gentile A, Memeo V. Single hepatocellular carcinoma ranging from 3 to 5 cm: radiofrequency ablation or resection? HPB (Oxford). 2007;9:429–34.CrossRefGoogle Scholar
- 16.Hong SN, Lee S-Y, Choi MS, Lee JH, Koh KC, Paik SW, Yoo BC, Rhee JC, Choi D, Lim HK, Lee K-W, Joh JW. Comparing the outcomes of radiofrequency ablation and surgery in patients with a single small hepatocellular carcinoma and well-preserved hepatic function. J Clin Gastroenterol. 2005;39:247–52.PubMedCrossRefGoogle Scholar
- 17.Vivarelli M, Guglielmi A, Ruzzenente A, Cucchetti A, Bellusci R, Cordiano C, Cavallari A. Surgical resection versus percutaneous radiofrequency ablation in the treatment of hepatocellular carcinoma on cirrhotic liver. Ann Surg. 2004;240:102–7.PubMedCentralPubMedCrossRefGoogle Scholar
- 18.Guglielmi A, Ruzzenente A, Valdegamberi A, Pachera S, Campagnaro T, D'Onofrio M, Martone E, Nicoli P, Iacono C. Radiofrequency ablation versus surgical resection for the treatment of hepatocellular carcinoma in cirrhosis. J Gastrointest Surg. 2008;12:192–8.PubMedCrossRefGoogle Scholar
- 19.White RR, Avital I, Sofocleous CT, Brown KT, Brody LA, Covey A, Getrajdman GI, Jarnagin WR, Dematteo RP, Fong Y, Blumgart LH, D'Angelica M. Rates and patterns of recurrence for percutaneous radiofrequency ablation and open wedge resection for solitary colorectal liver metastasis. J Gastrointest Surg. 2007;11:256–63.PubMedCrossRefGoogle Scholar
- 20.Peng Z-W, Zhang Y-J, Chen M-S, Xu L, Liang H-H, Lin X-J, Guo R-P, Zhang Y-Q, Lau WY. Radiofrequency ablation with or without transcatheter arterial chemoembolization in the treatment of hepatocellular carcinoma: a prospective randomized trial. J Clin Oncol. 2013;31:426–32.PubMedCrossRefGoogle Scholar
- 21.Maluccio M, Covey AM, Gandhi R, Gonen M, Getrajdman GI, Brody LA, Fong Y, Jarnagin W, D'Angelica M, Blumgart L, DeMatteo R, Brown KT. Comparison of survival rates after bland arterial embolization and ablation versus surgical resection for treating solitary hepatocellular carcinoma up to 7cm. J Vasc Interv Radiol. 2005;16:955–61.PubMedCrossRefGoogle Scholar
- 22.Yamakado K, Nakatsuka A, Takaki H, Yokoi H, Usui M, Sakurai H, Isaji S, Shiraki K, Fuke H, Uemoto S, Takeda K. Early-stage hepatocellular carcinoma: radiofrequency ablation combined with chemoembolization versus hepatectomy. Radiology. 2008;247:260–6.PubMedCrossRefGoogle Scholar
- 23.Yamagiwa K, Shiraki K, Yamakado K, Mizuno S, Hori T, Yagi S, Hamada T, Iida T, Nakamura I, Fujii K, Usui M, Isaji S, Ito K, Tagawa S, Takeda K, Yokoi H, Noguchi T. Survival rates according to the Cancer of the Liver Italian Program scores of 345 hepatocellular carcinoma patients after multimodality treatments during a 10-year period in a retrospective study. J Gastroenterol Hepatol. 2008;23:482–90.PubMedCrossRefGoogle Scholar
- 24.Wei AC, Greig PD, Grant D, Taylor B, Langer B, Gallinger S. Survival after hepatic resection for colorectal metastases: a 10-year experience. Ann Surg Oncol. 2006;13:668–76.PubMedCrossRefGoogle Scholar
- 25.Gallagher DJ, Kemeny N. Metastatic colorectal cancer: from improved survival to potential cure. Oncology. 2010;78:237–48.PubMedCrossRefGoogle Scholar
- 26.Sgouros J, Cast J, Garadi KK, Belechri M, Breen DJ, Monson JR, Maraveyas A. Chemotherapy plus percutaneous radiofrequency ablation in patients with inoperable colorectal liver metastases. World J Gastrointest Oncol. 2011;3:60–6.PubMedCentralPubMedCrossRefGoogle Scholar
- 27.Abitabile P, Hartl U, Lange J, Maurer CA. Radiofrequency ablation permits an effective treatment for colorectal liver metastasis. Eur J Surg Oncol. 2007;33:67–71.PubMedCrossRefGoogle Scholar
- 28.Wu Y-Z, Li B, Wang T, Wang S-J, Zhou Y-M. Radiofrequency ablation vs hepatic resection for solitary colorectal liver metastasis: a meta-analysis. World J Gastroenterol. 2011;17:4143–8.PubMedCentralPubMedCrossRefGoogle Scholar
- 29.Fong ZV, Palazzo F, Needleman L, Brown DB, Eschelman DJ, Chojnacki KA, Yeo CJ, Rosato EL. Combined hepatic arterial embolization and hepatic ablation for unresectable colorectal metastases to the liver. Am Surg. 2012;78:1243–8.PubMedGoogle Scholar
- 30.Sarmiento JM, Heywood G, Rubin J, Ilstrup DM, Nagorney DM, Que FG. Surgical treatment of neuroendocrine metastases to the liver: a plea for resection to increase survival. J Am Coll Surg. 2003;197:29–37.PubMedCrossRefGoogle Scholar
- 31.Montorsi M, Santambrogio R, Bianchi P, Donadon M, Moroni E, Spinelli A, Costa M. Survival and recurrences after hepatic resection or radiofrequency for hepatocellular carcinoma in cirrhotic patients: a multivariate analysis. J Gastrointest Surg. 2005;9:62–7; discussion 67–8.PubMedCrossRefGoogle Scholar
- 32.Ogihara M, Wong LL, Machi J. Radiofrequency ablation versus surgical resection for single nodule hepatocellular carcinoma: long-term outcomes. HPB (Oxford). 2005;7:214–21.CrossRefGoogle Scholar
- 33.Abu-Hilal M, Primrose JN, Casaril A, McPhail MJW, Pearce NW, Nicoli N. Surgical resection versus radiofrequency ablation in the treatment of small unifocal hepatocellular carcinoma. J Gastrointest Surg. 2008;12:1521–6.PubMedCrossRefGoogle Scholar
- 34.Nanashima A, Tobinaga S, Masuda J, Miyaaki H, Taura N, Takeshita H, Hidaka S, Sawai T, Nakao K, Nagayasu T. Selecting treatment for hepatocellular carcinoma based on the results of hepatic resection and local ablation therapy. J Surg Oncol. 2010;101:481–5.PubMedCrossRefGoogle Scholar
- 35.Nishikawa H, Inuzuka T, Takeda H, Nakajima J, Matsuda F, Sakamoto A, Henmi S, Hatamaru K, Ishikawa T, Saito S, Nasu A, Kita R, Kimura T, Arimoto A, Osaki Y. Comparison of percutaneous radiofrequency thermal ablation and surgical resection for small hepatocellular carcinoma. BMC Gastroenterol. 2011;11:143.PubMedCentralPubMedCrossRefGoogle Scholar
- 36.Hung H-H, Chiou Y-Y, Hsia C-Y, Su C-W, Chou Y-H, Chiang J-H, Kao W-Y, Huo T-I, Huang Y-H, Su Y-H, Lin H-C, Lee S-D, Wu J-C. Survival rates are comparable after radiofrequency ablation or surgery in patients with small hepatocellular carcinomas. Clin Gastroenterol Hepatol. 2011;9:79–86.PubMedCrossRefGoogle Scholar
- 37.Wang J-H, Wang C-C, Hung C-H, Chen C-L, Lu S-N. Survival comparison between surgical resection and radiofrequency ablation for patients in BCLC very early/early stage hepatocellular carcinoma. J Hepatol. 2012;56:412–8.PubMedCrossRefGoogle Scholar
- 38.Feng K, Yan J, Li X, Xia F, Ma K, Wang S, Bie P, Dong J. A randomized controlled trial of radiofrequency ablation and surgical resection in the treatment of small hepatocellular carcinoma. J Hepatol. 2012;57:794–802.PubMedCrossRefGoogle Scholar
- 39.Peng Z-W, Lin X-J, Zhang Y-J, Liang H-H, Guo R-P, Shi M, Chen M-S. Radiofrequency ablation versus hepatic resection for the treatment of hepatocellular carcinomas 2 cm or smaller: a retrospective comparative study. Radiology. 2012;262:1022–33.PubMedCrossRefGoogle Scholar
- 40.Kagawa T, Koizumi J, Kojima S-i, Nagata N, Numata M, Watanabe N, Watanabe T, Mine T. Transcatheter arterial chemoembolization plus radiofrequency ablation therapy for early stage hepatocellular carcinoma: comparison with surgical resection. Cancer. 2010;116:3638–44.PubMedCrossRefGoogle Scholar
- 41.Tashiro H, Aikata H, Waki K, Amano H, Oshita A, Kobayashi T, Tanimoto Y, Kuroda S, Tazawa H, Chayama K, Asahara T, Ohdan H. Treatment strategy for early hepatocellular carcinomas: comparison of radiofrequency ablation with or without transcatheter arterial chemoembolization and surgical resection. J Surg Oncol. 2011;104:3–9.PubMedCrossRefGoogle Scholar
- 42.Oshowo A, Gillams A, Harrison E, Lees WR, Taylor I. Comparison of resection and radiofrequency ablation for treatment of solitary colorectal liver metastases. Br J Surg. 2003;90:1240–3.PubMedCrossRefGoogle Scholar
- 43.Abdalla EK, Vauthey J-N, Ellis LM, Ellis V, Pollock R, Broglio KR, Hess K, Curley SA. Recurrence and outcomes following hepatic resection, radiofrequency ablation, and combined resection/ablation for colorectal liver metastases. Ann Surg. 2004;239:818–25; discussion 825–7.PubMedCentralPubMedCrossRefGoogle Scholar
- 44.Aloia TA, Vauthey J-N, Loyer EM, Ribero D, Pawlik TM, Wei SH, Curley SA, Zorzi D, Abdalla EK. Solitary colorectal liver metastasis: resection determines outcome. Arch Surg. 2006;141:460–6; discussion 466–7.PubMedCrossRefGoogle Scholar
- 45.Park IJ, Kim HC, Yu CS, Kim PN, Won HJ, Kim JC. Radiofrequency ablation for metachronous liver metastasis from colorectal cancer after curative surgery. Ann Surg Oncol. 2008;15:227–32.PubMedCrossRefGoogle Scholar
- 46.Berber E, Tsinberg M, Tellioglu G, Simpfendorfer CH, Siperstein AE. Resection versus laparoscopic radiofrequency thermal ablation of solitary colorectal liver metastasis. J Gastrointest Surg. 2008;12:1967–72.PubMedCrossRefGoogle Scholar
- 47.Lee W-S, Yun SH, Chun H-K, Lee WY, Kim S-J, Choi S-H, Heo J-S, Joh JW, Choi D, Kim S-H, Rhim H, Lim H-K. Clinical outcomes of hepatic resection and radiofrequency ablation in patients with solitary colorectal liver metastasis. J Clin Gastroenterol. 2008;42:945–9.PubMedCrossRefGoogle Scholar
- 48.Hur H, Ko YT, Min BS, Kim KS, Choi JS, Sohn SK, Cho CH, Ko HK, Lee JT, Kim NK. Comparative study of resection and radiofrequency ablation in the treatment of solitary colorectal liver metastases. Am J Surg. 2009;197:728–36.PubMedCrossRefGoogle Scholar
- 49.Reuter NP, Woodall CE, Scoggins CR, McMasters KM, Martin RCG. Radiofrequency ablation vs. resection for hepatic colorectal metastasis: therapeutically equivalent? J Gastrointest Surg. 2009;13:486–91.PubMedCrossRefGoogle Scholar
- 50.McKay A, Fradette K, Lipschitz J. Long-term outcomes following hepatic resection and radiofrequency ablation of colorectal liver metastases. HPB Surg. 2009;2009:346863.PubMedCentralPubMedCrossRefGoogle Scholar
- 51.Otto G, Düber C, Hoppe-Lotichius M, König J, Heise M, Pitton MB. Radiofrequency ablation as first-line treatment in patients with early colorectal liver metastases amenable to surgery. Ann Surg. 2010;251:796–803.PubMedCrossRefGoogle Scholar
- 52.Schiffman SC, Bower M, Brown RE, Martin RCG, McMasters KM, Scoggins CR. Hepatectomy is superior to thermal ablation for patients with a solitary colorectal liver metastasis. J Gastrointest Surg. 2010;14:1881–6; discussion 1886–7.PubMedCrossRefGoogle Scholar
- 53.Lee KH, Kim HO, Yoo CH, Son BH, Park YL, Cho YK, Kim H, Han WK. Comparison of radiofrequency ablation and resection for hepatic metastasis from colorectal cancer. Korean J Gastroenterol. 2012;59:218–23.PubMedCrossRefGoogle Scholar
- 54.Livraghi T, Goldberg SN, Solbiati L, Meloni F, Ierace T, Gazelle GS. Percutaneous radio-frequency ablation of liver metastases from breast cancer: initial experience in 24 patients. Radiology. 2001;220:145–9.PubMedCrossRefGoogle Scholar
- 55.Lawes D, Chopada A, Gillams A, Lees W, Taylor I. Radiofrequency ablation (RFA) as a cytoreductive strategy for hepatic metastasis from breast cancer. Ann R Coll Surg Engl. 2006;88:639–42.PubMedCentralPubMedCrossRefGoogle Scholar
- 56.Sofocleous CT, Nascimento RG, Gonen M, Theodoulou M, Covey AM, Brody LA, Solomon SM, Thornton R, Fong Y, Getrajdman GI, Brown KT. Radiofrequency ablation in the management of liver metastases from breast cancer. AJR Am J Roentgenol. 2007;189:883–9.PubMedCrossRefGoogle Scholar
- 57.Gunabushanam G, Sharma S, Thulkar S, Srivastava DN, Rath GK, Julka PK, Bhatnagar S. Radiofrequency ablation of liver metastases from breast cancer: results in 14 patients. J Vasc Interv Radiol. 2007;18:67–72.PubMedCrossRefGoogle Scholar
- 58.Jakobs TF, Hoffmann R-T, Schrader A, Stemmler HJ, Trumm C, Lubienski A, Murthy R, Helmberger TK, Reiser MF. CT-guided radiofrequency ablation in patients with hepatic metastases from breast cancer. Cardiovasc Intervent Radiol. 2009;32:38–46.PubMedCrossRefGoogle Scholar
- 59.Meloni MF, Andreano A, Laeseke PF, Livraghi T, Sironi S, Lee FT. Breast cancer liver metastases: US-guided percutaneous radiofrequency ablation–intermediate and long-term survival rates. Radiology. 2009;253:861–9.PubMedCentralPubMedCrossRefGoogle Scholar
- 60.Gillams A, Cassoni A, Conway G, Lees W. Radiofrequency ablation of neuroendocrine liver metastases: the Middlesex experience. Abdom Imaging. 2005;30:435–41.PubMedCrossRefGoogle Scholar
- 61.Mazzaglia PJ, Berber E, Milas M, Siperstein AE. Laparoscopic radiofrequency ablation of neuroendocrine liver metastases: a 10-year experience evaluating predictors of survival. Surgery. 2007;142:10–9.PubMedCrossRefGoogle Scholar
- 62.Akyildiz HY, Mitchell J, Milas M, Siperstein A, Berber E. Laparoscopic radiofrequency thermal ablation of neuroendocrine hepatic metastases: long-term follow-up. Surgery. 2010;148:1288–93; discussion 1293.PubMedCrossRefGoogle Scholar
- 63.Yamakado K, Nakatsuka A, Takaki H, Mori Y, Tonouchi H, Kusunoki M, Kida H, Takeda K. Prospective study of arterial infusion chemotherapy followed by radiofrequency ablation for the treatment of liver metastasis of gastric cancer. J Vasc Interv Radiol. 2005;16:1747–51.PubMedCrossRefGoogle Scholar
- 64.Kim HR, Cheon SH, Lee K-H, Ahn JR, Jeung H-C, Lee SS, Chung HC, Noh SH, Rha SY. Efficacy and feasibility of radiofrequency ablation for liver metastases from gastric adenocarcinoma. Int J Hyperthermia. 2010;26:305–15.PubMedCrossRefGoogle Scholar
- 65.Mylona S, Stroumpouli E, Pomoni M, Galani P, Ntai S, Thanos L. Radiofrequency ablation of liver metastases from cancer of unknown primary site. Diagn Interv Radiol. 2009;15:297–302.PubMedGoogle Scholar
- 66.Gervais DA, Arellano RS, Mueller PR. Percutaneous radiofrequency ablation of ovarian cancer metastasis to the liver: indications, outcomes, and role in patient management. AJR Am J Roentgenol. 2006;187:746–50.PubMedCrossRefGoogle Scholar
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