Chapter

Trends in Veterinary Sciences

pp 135-139

Date:

Canine Erythrocyte Morphology: Observations of a New Pattern, the “Quatrefoil” Erythrocyte

  • George LubasAffiliated withDipartimento di Scienze Veterinarie, Università di Pisa Email author 
  • , Alessandra GavazzaAffiliated withDipartimento di Scienze Veterinarie, Università di Pisa
  • , Biancaurora GugliucciAffiliated withDipartimento di Scienze Veterinarie, Università di Pisa
  • , Anna PasquiniAffiliated withDipartimento di Scienze Veterinarie, Università di Pisa
  • , Marianna RicciAffiliated withDipartimento di Scienze Veterinarie, Università di Pisa

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Abstract

The “quatrefoil” erythrocyte pattern may be observed during erythrocyte morphology evaluation in canine complete blood counts (CBCs). “Quatrefoil” red blood cells (RBCs) have been documented in blood smears using both optical and scanning electron microscopy. In our examination of 3,958 CBCs, we found a prevalence of 3.89 % “quatrefoil” RBCs. These RBCs mostly occurred between the body and feathered edge of the blood smears. This pattern was not statistically related to the breed or sex, but to the age of the dog (older dogs; p < 0.0001). “Quatrefoil” RBCs are not significantly associated with other morphological erythrocyte changes. However, compared with populations of dogs without “quatrefoil” RBCs, dogs with this RBC pattern are significantly more likely to exhibit lower total leukocyte and neutrophil counts. Hypotheses describing the origin of “quatrefoil” RBCs include artifact effects, dacryocyte overlapping, and the effect of adhesion forces between two circulating RBCs in the blood stream (i.e., tank-trading and/or tumbling).

Keywords

Erythrocyte Morphology Poikilocytosis Dog Quatrefoil erythrocyte