A Comparison of Network Characteristics in Metabolic and Manufacturing Systems
Both metabolic and manufacturing systems face fluctuating environmental influences and thus share the common challenge to maintain a high level of efficiency for a variety of different conditions. Therefore, transferring methods used for analyzing one of the systems can lead to gaining new insights in the other. Following-up on previous findings on analogies in metabolic and manufacturing systems, our approach now is to analyze and compare complex network measures such as centrality or flow activity in both systems to identify quantified relations. The results show that both systems also display distinct statistical differences in addition to their various structural similarities.
We thank Nikolaus Sonnenschein (UC San Diego) for the simulation data of metabolic fluxes and for providing a curated metabolic network structure. The research of Katja Windt is supported by the Alfried Krupp Prize for Young University Teachers of the Krupp Foundation. Marc Hütt acknowledges support from Deutsche Forschungsgemeinschaft (grant HU-937/6).
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