Advertisement

MRI Estimation of T1 Relaxation Time Using a Constrained Optimization Algorithm

  • Fang Cao
  • Olivier Commowick
  • Elise Bannier
  • Jean-Christophe Ferré
  • Gilles Edan
  • Christian Barillot
Part of the Lecture Notes in Computer Science book series (LNCS, volume 7509)

Abstract

We propose a new method to improve T 1 mapping with respect to the popular DESPOT1 algorithm. A distance function is defined to model the distance between the pure signal and the measurements in presence of noise. We use a constrained gradient descent optimization algorithm to iteratively find the optimal values of T 1 and M 0. The method is applied to MR images acquired with 2 gradient echo sequences and different flip angles. The performance of T 1 mapping is evaluated both on phantom and on in vivo experiments.

Keywords

T1 relaxometry DESPOT1 quantitative analysis MRI 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Bagher-Ebadian, H., Jain, R., Paudyal, R., Nejad-Davarani, S.P., Narang, J., Jiang, Q., Mikkelsen, T., Ewing, J.R.: Magnetic resonance estimation of longitudinal relaxation time (T1) in spoiled gradient echo using an adaptive neural network. In: IJCNN, pp. 2557–2562 (2011)Google Scholar
  2. 2.
    Cao, F., Commowick, O., Bannier, E., Crimi, A., Barillot, C.: T1 and T2 mapping in patients with multiple sclerosis for project USPIO–6. In: ARSEP (June 2012)Google Scholar
  3. 3.
    Christensen, K.A., Grant, D.M., Schulman, E.M., Walling, C.: Optimal determination of relaxation times of fourier transform nuclear magnetic resonance. determination of spin-lattice relaxation times in chemically polarized species. J. Phys. Chem. 78(19), 1971–1977 (1974)CrossRefGoogle Scholar
  4. 4.
    Dagia, C., Ditchfield, M.: 3t mri in paediatrics: challenges and clinical applications. Eur. J. Radiol. 68(2), 309–319 (2008)CrossRefGoogle Scholar
  5. 5.
    Deichmann, R., Hahn, D., Haase, A.: Fast T1 mapping on a whole-body scanner. MRM 42(1), 206–209 (1999)Google Scholar
  6. 6.
    Deoni, S., Rutt, B., Peters, T.: Rapid combined T1 and T2 mapping using gradient recalled acquisition in the steady state. MRM 49(3), 515–526 (2003)Google Scholar
  7. 7.
    Deoni, S.C.L., Peters, T.M., Rutt, B.K.: Determination of optimal angles for variable nutation proton magnetic spin-lattice, T1, and spin-spin, T2, relaxation times measurement. MRM 51(1), 194–199 (2004)Google Scholar
  8. 8.
    Ferré, J.C., Tourbah, A., Berry, I., Barillot, C., Freeman, L., Galanaud, D., Maarouf, A., Pelletier, J., Portefaix, C., Ranjeva, J.P., Wiest-Daesslé, N., Edan, G.: MRI USPIO analysis in 35 clinically isolated syndrome patients. In: ECTRIMS 2011 vol. (5), pp. 399–416 (2011)Google Scholar
  9. 9.
    Gelman, N., Gorell, J., Barker, P., Savage, R., Spickler, E., Windham, J., Knight, R.: MR imaging of human brain at 3.0T: preliminary report on transverse relaxation rates and relation to estimated iron content. Radiology 210(3), 759–767 (1999)Google Scholar
  10. 10.
    Lee, C., Baker, E., Thomasson, D.: Normal Regional T1 and T2 Relaxation Times of the Brain at 3T, p. 959 (2006)Google Scholar
  11. 11.
    Ollivro, S., Eliat, P., Hitti, E., Tran, L., de Certaines, J., Saint-Jalmes, H.: Preliminary MRI quality assessment and device acceptance guidelines for a multicenter bioclinical study: The GO glioblastoma project. J. Neuroimaging (2011)Google Scholar
  12. 12.
    Stanisz, G., Odrobina, E., Pun, J., Escaravage, M., Graham, S., Bronskill, M., Henkelman, R.: T1, T2 relaxation and magnetization transfer in tissue at 3T. MRM 54(3), 507–512 (2005)Google Scholar
  13. 13.
    Tofts, P.: Quantitative MRI of the Brain: Measuring Changes Caused by Disease. John Wiley & Sons, Ltd. (2003)Google Scholar
  14. 14.
    Vaithianathar, L., Tench, C.R., Morgan, P.S., Constantinescu, C.S.: Magnetic resonance imaging of the cervical spinal cord in multiple sclerosis–a quantitative T1 relaxation time mapping approach. J. Neurology 250(3), 307–315 (2003)CrossRefGoogle Scholar
  15. 15.
    Wang, H.Z., Riederer, S.J., Lee, J.N.: Optimizing the precision in T1 relaxation estimation using limited flip angles. MRM 5(5), 399–416 (1987)Google Scholar
  16. 16.
    Wang, J., Qiu, M., Kim, H., Constable, R.T.: T1 measurements incorporating flip angle calibration and correction in vivo. J. Magn. Reson. 182(2), 283–292 (2006)CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Fang Cao
    • 1
  • Olivier Commowick
    • 1
  • Elise Bannier
    • 1
  • Jean-Christophe Ferré
    • 2
  • Gilles Edan
    • 2
  • Christian Barillot
    • 1
  1. 1.IRISA UMR CNRS 6074VisAGeS U746 INSERM/INRIARennesFrance
  2. 2.University hospital PontchaillouRennesFrance

Personalised recommendations