Experimental

Chapter
Part of the Springer Theses book series (Springer Theses)

Abstract

For rapid screening of conditions and substrates, reactions were frequently carried out using a Radley’s 12 port reaction carousel with reduced volume tubes. However results were identical when repeated using standard Schlenk techniques. All glassware was washed in acid (conc. HNO3) and base baths (iPrOH/KOH) before being rinsed (H2O/acetone) and oven-dried at 150 °C for at least 18 h. Dry solvents were purchased (Aldrich, Fluka, Alfa Aesar) and distilled or obtained by passage through an Anhydrous Engineering drying column. Solvents for extraction and chromatography were technical grade. Carbon monoxide was purchased from BOC. Purchased chemicals (Aldrich, Acros, Fluka, Alfa Aesar) were used as received, unless otherwise stated. Reagents requiring purification were done so according to Purification of Laboratory. Benzoquinone was sublimed before use.

Keywords

Methyl Aniline Nbutyl Acrylate Gastight Syringe Phenylacetyl Chloride Palladium Dichloride 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Perrin DD, Armarego WLF (1988) Purification of laboratory chemicals, 3rd edn. Butterworth Heinemann, OxfordGoogle Scholar
  2. 2.
    Wagar R, Brown JM (2008) Angew Chem Int Ed 47:4228–4230CrossRefGoogle Scholar
  3. 3.
    Iwakura Y, Izawa S-IJ (1964) Org Chem 29:379–382CrossRefGoogle Scholar
  4. 4.
    Azad S, Kumamoto K, Uegaki K, Ichikawa Y, Kotsuki H (2006) Tetrahedron Lett 47:587–590CrossRefGoogle Scholar
  5. 5.
    Franz RA et al (1962) J Org Chem 27:4341–4346CrossRefGoogle Scholar
  6. 6.
    Synder JK, Stock LMJ (1980) Org Chem 45:886–891CrossRefGoogle Scholar
  7. 7.
    Lengyei I, Stephani RA, Patel H (2007) J Heterocycles 73:349–375CrossRefGoogle Scholar
  8. 8.
    Fikes LE, Shechter HJ (1979) Org Chem 44:741–744CrossRefGoogle Scholar
  9. 9.
    Oh HK, Park JE, Sung DD, Lee IJ (2004) Org Chem 69:3150–3153CrossRefGoogle Scholar
  10. 10.
    Mukiyama T et al (1967) J Org Chem 32:3475–3477CrossRefGoogle Scholar
  11. 11.
    Thavonekham B (1997) Synthesis 10:1189–1194CrossRefGoogle Scholar
  12. 12.
    Kurth TL, Lewis FDJ (2003) Am Chem Soc 45:13760–13767CrossRefGoogle Scholar
  13. 13.
    Drent E, Broekhoven JAM, Doyle MJJ (1991) Organomet Chem 417:235–240CrossRefGoogle Scholar
  14. 14.
    Hegarty AF, Bruice TCJ (1970) Am Chem Soc 92:6575–6588CrossRefGoogle Scholar
  15. 15.
    Krantz A, Spencer RW, Tam TF, Liak T-J, Copp LJ, Thomas EM, Rafferty SPJ (1990) Med Chem 33:464–479CrossRefGoogle Scholar
  16. 16.
    Molina P, Alajarin M, Vidal A (1989) Tetrahedron 31:4263–4286CrossRefGoogle Scholar
  17. 17.
    Sheehan JC, Davies GDJ (1964) Org Chem 29:3599–3601CrossRefGoogle Scholar
  18. 18.
    Staiger RP, Wanger ECJ (1959) Org Chem 18:1427–1439CrossRefGoogle Scholar
  19. 19.
    Bottaro JC, Penwell PE, Schmitt RJ (1991) J Org Chem 56:1305–1307Google Scholar
  20. 20.
    Bortnick NB, Luskin LS, Hurwitz MD, Craig WE, Mirza JJ (1956) Am Chem Soc 78:4039–4042CrossRefGoogle Scholar
  21. 21.
    Clayden J, Helliwell M, McCarthy C, Westlund NJ (2000) Chem Soc Perkin Trans 1:3232–3249Google Scholar
  22. 22.
    Song B, Wang S, Sun C, Deng H, Xu B (2007) Tetrahedron Lett 48:8982–8986CrossRefGoogle Scholar
  23. 23.
    Moriarty RM, Chany CJ, Vaid RK, Prakash O, Tuladhar SMJ (1993) Org Chem 58:2478–2482CrossRefGoogle Scholar
  24. 24.
    Selva M, Tundo P, Perosa A, Dall’Acqua FJ (2005) Org Chem 70:2771–2777CrossRefGoogle Scholar
  25. 25.
    Pirkle WH, Simmons KA, Boeder CWJ (1979) Org Chem 44:4891–4896CrossRefGoogle Scholar
  26. 26.
    Bratt MO, Taylor PCJ (2003) Org Chem 68:5439–5444CrossRefGoogle Scholar
  27. 27.
    Aresta M, Berloco C, Quaranta E (1995) Tetrahedron 51:8073–8088CrossRefGoogle Scholar
  28. 28.
    Sumiyoshi H, Shimizu T, Katoh M, Baba Y, Sodeoka M (2002) Org Lett 4:3923–3926CrossRefGoogle Scholar
  29. 29.
    De Risi C, Ferraro L, Pollini GP, Tanganelli S, Valente F, Veronese AC (2008) Bioorganic Med Chem 16:9904–9910CrossRefGoogle Scholar
  30. 30.
    Manikowski A, Kolarska Z (2009) Synth Commun 39:3621–3638CrossRefGoogle Scholar
  31. 31.
    Lozanova AV, Ugurchieva TM, Veselovsky VV (2008) Russ Chem B 57:1753–1755Google Scholar
  32. 32.
    Creary XJ (1980) Org Chem 45:2419–2425CrossRefGoogle Scholar
  33. 33.
    Bodnar BS, Vogt PFJ (2009) Org Chem 74:2598–2600CrossRefGoogle Scholar
  34. 34.
    Bell IM, Abell C, Leeper FJJ (1994) Chem Soc Perkin Trans 1:1997–2006Google Scholar
  35. 35.
    Salerno CP, Magde D, Patron APJ (2000) Org Chem 65:3971–3981CrossRefGoogle Scholar
  36. 36.
    Durandetti M, Gosmini C, Périchon J (2007) Tetrahedron 63:1146–1153CrossRefGoogle Scholar
  37. 37.
    Li JH, Liang Y, Wang DP, Liu WJ, Xie YX, Yin DL (2005) J Org Chem 70:2832–2834Google Scholar
  38. 38.
    Chen Q-H, Rao PNP, Knaus EE (2005) Bioorganic Med Chem 13:4694–4703CrossRefGoogle Scholar
  39. 39.
    Pei T, Wang X, Widenhoefer RA (2002) J Am Chem Soc 125:648–649CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Royal Society of ChemistryThomas Graham HouseCambridgeUK

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