Abstract
Choroidal neovascular membranes (CNVs) most commonly occur with age-related macular degeneration (ARMD). Features of ‘dry’ AMD include hard drusen, soft drusen, retinal pigment epithelial disruption and geographic atrophy. Patients with extensive small drusen, non-extensive intermediate size drusen or pigment abnormalities have only a 1.3 % 5-year probability of progression to advanced AMD according to the ARED Study (Age-Related Eye Disease Study Research Group 2001). Those with extensive intermediate size drusen, at least one large druse, noncentral geographic atrophy in one or both eyes, or advanced AMD or vision loss due to AMD in one eye, are at risk of vision loss from advanced AMD in up to 50 % (large drusen with pigmentary changes) after 5 years (Ferris et al. 2005).
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Williamson, T.H. (2013). Choroidal Neovascular Membrane. In: Vitreoretinal Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31872-6_11
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