BNCT for Advanced or Recurrent Head and Neck Cancer

Chapter

Abstract

The therapeutic effect of surgery and/or combination of conventional chemoradiotherapy is limited in the patients with recurrent squamous cell carcinoma (SCC) and locally advanced non-SCC of the head and neck. Currently, clinical trials of BNCT for head and neck cancers are being conducted in some institutes to verify its usefulness. BNCT was performed in ten patients with recurrent SCC, seven patients with recurrent non-SCC, and three patients with newly diagnosed non-SCC in our university between October 2003 and September 2007. Eleven patients showed complete remission, and seven patients showed partial remission of irradiated site. The effective rate [(CR + PR)/total cases] was 90 %. No severe acute or chronic normal tissue reactions were observed in any patients. BNCT is effective and safe in the patients with recurrent SCC and locally advanced non-SCC.

Keywords

Partial Remission Adenoid Cystic Carcinoma Boron Concentration Linear Energy Transfer Gold Wire 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of Otolaryngology, Head and Neck SurgeryKawasaki Medical SchoolOkayamaJapan

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