Conclusions

  • Thomas  E. Ouldridge
Chapter
Part of the Springer Theses book series (Springer Theses)

Abstract

This thesis introduces a novel coarse-grained model of DNA which is specifically designed to capture the structural, mechanical and thermodynamic properties associated with single-stranded and duplex DNA, and the transition between the two. The model has been shown to give a physically reasonable description of a range of DNA properties, and has been applied to two nanotechnological systems (DNA tweezers and a two-footed DNA walker). These studies represent the first investigations into dynamic DNA devices using a coarse-grained model.

Keywords

Single Strand Sequence Dependence Displacement Process Strand Displacement Duplex Formation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Thomas  E. Ouldridge
    • 1
  1. 1.University of OxfordOxfordUK

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