Objective Means of Diagnosing Anorexia Nervosa and Bulimia Nervosa in Hair

Chapter

Abstract

The measurement of stable isotope ratios in hair has the potential to provide a unique method for objectively diagnosing individuals with eating disorders. When the body is in an anabolic state, it incorporates dietary proteins into growing hair. Likewise, when the body becomes catabolic, the 15N/14N ratio of the individual’s tissues increases further due to something functionally similar to an increase in trophic level. As the individual loses weight, the individual’s body consumes its own energy and protein stores. The remaining proteins are 15N-enriched, and their amino acids are recycled. Some of these amino acids are incorporated into new hair growth, providing a signal of the change in diet.

Also SEM microanalysis was used to assess hair concentration of calcium (Ca), sulphur (S) and silicon (Si) in patients with anorexia nervosa and its change with improvement of nutritional status.

Keywords

Anorexia Nervosa Trophic Level Eating Disorder Bulimia Nervosa Hair Growth 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Hatch KA et al (2006) An objective means of diagnosing anorexia nervosa and bulimia nervosa using 15N/14N and 13C/12C ratios in hair. Rapid Commun Mass Spectrom 20:3367–3373PubMedCrossRefGoogle Scholar
  2. 2.
    Sponheimer M et al (2005) An experimental study of nitrogen flux in llamas: is 14N preferentially excreted? J Archaeol Sci 30:1649–1655CrossRefGoogle Scholar
  3. 3.
    Mekota A-M (2006) Serial analysis of stable nitrogen and carbon isotopes in hair: monitoring starvation and recovery phases of patients suffering from anorexia nervosa. Rapid Commun Mass Spectrom 20:1604–1610PubMedCrossRefGoogle Scholar
  4. 4.
    Fuller BT et al (2005) Nitrogen balance and delta15N: why you’re not what you eat during nutritional stress. Rapid Commun Mass Spectrom 19:2497–2506PubMedCrossRefGoogle Scholar
  5. 5.
    Huse DM, Lucas AR (1984) Dietary patterns in anorexia nervosa. Am J Clin Nutr 40(2):251–254PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.FerraraItaly

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