The brain is one of the most common sites of cancer metastasis, and radiation, in conjunction with surgery and steroid therapy, is a cornerstone of management of brain metastases. Whole brain radiation therapy (WBRT) using conventional external beam radiation is most commonly employed. Stereotactic radiosurgery (SRS) can be used in the adjuvant or upfront settings for patients with limited number of intracranial metastatic foci, sufficient extracranial disease control, and appropriate performance status.
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