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Applying AIBench Framework to Develop Rich User Interfaces in NGS Studies

  • Hugo López-Fernández
  • Daniel Glez-Peña
  • Miguel Reboiro-Jato
  • Gonzalo Gómez-López
  • David G. Pisano
  • Florentino Fdez-Riverola
Part of the Advances in Intelligent and Soft Computing book series (AINSC, volume 154)

Abstract

AIBench is a Java application framework for building translational software in Biomedicine. In this paper, we show how to use this framework to develop rich user interfaces in next-generation sequencing (NGS) experiments. In particular, we present PileLineGUI, a desktop environment for handling genome position files in next-generation studies based on the PileLine command-line toolbox.

Keywords

next-generation sequencing pileup vcf single nucleotide variants PileLine AIBench framework 

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References

  1. 1.
    The International Cancer Genome Consortium. Nature 464(7291), 993–998 (2010)Google Scholar
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    Glez-Peña, D., Gómez-López, G., Reboiro-Jato, M., Fdez-Riverola, F., Gómez-Pisano, D.: PileLine: a toolbox to handle genome position information in next-generation sequencing studies. BMC Bioinformatics 12, 31 (2011)CrossRefGoogle Scholar
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    Glez-Peña, D., López-Fernández, H., Reboiro-Jato, M., Méndez, J.R., Fdez-Riverola, F.: A Java application framework for scientific software development. John Wiley & Sons, Ltd. (2011)Google Scholar
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    López-Fernández, H., Glez-Peña, D., Reboiro-Jato, M., Gómez-López, G., Gómez Pisano, D., Fdez-Riverola, F.: PileLineGUI: a desktop environment for handling genome position files in next-generation sequencing studies. Nucleic Acids Research Web Server (1-5) (2011)Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Hugo López-Fernández
    • 1
  • Daniel Glez-Peña
    • 1
  • Miguel Reboiro-Jato
    • 1
  • Gonzalo Gómez-López
    • 2
  • David G. Pisano
    • 2
  • Florentino Fdez-Riverola
    • 1
  1. 1.ESEI: Escuela Superior de Ingeniería InformáticaUniversity of VigoOurenseSpain
  2. 2.Bioinformatics Unit (UBio), Biología Estructural y BiocomputaciónCentro Nacional de Investigaciones Oncológicas (CNIO)MadridSpain

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