Modeling of Membrane Proteins

  • Dorota LatekEmail author
  • Bartosz Trzaskowski
  • Szymon Niewieczerzał
  • Przemysław Miszta
  • Krzysztof Młynarczyk
  • Aleksander Debinski
  • Wojciech Puławski
  • Shuguang Yuan
  • Sławomir Filipek
Part of the Springer Series in Bio-/Neuroinformatics book series (SSBN, volume 1)


The membrane proteins are still the “Wild West” of structural biology. Although more and more membrane proteins structures are determined, their functioning is still difficult to investigate because they are fully functional only in the membranous environments. Several specific methodologies were developed to investigate various aspects of their cellular life but still they are challenging for computational methods. In this chapter we summarize the efforts made on elucidation the structural and dynamical properties of different types of membrane proteins emphasizing on those computational methods which were designed and employed particularly to study membrane proteins including their interactions in complex membranous systems.


Steer Molecular Dynamics Membrane Protein Structure Steer Molecular Dynamics Simulation Contact Prediction Helical Membrane Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Dorota Latek
    • 1
    Email author
  • Bartosz Trzaskowski
    • 2
  • Szymon Niewieczerzał
    • 1
  • Przemysław Miszta
    • 1
    • 3
  • Krzysztof Młynarczyk
    • 2
  • Aleksander Debinski
    • 2
  • Wojciech Puławski
    • 2
    • 4
  • Shuguang Yuan
    • 1
    • 5
  • Sławomir Filipek
    • 2
  1. 1.International Institute of Molecular and Cell BiologyWarsawPoland
  2. 2.Faculty of ChemistryUniversity of WarsawWarsawPoland
  3. 3.Institute of Physics, Faculty of Mathematics, Physics & Technical SciencesKazimierz Wielki University in BydgoszczBydgoszczPoland
  4. 4.Institute of Biochemistry and Biophysics PASWarsawPoland
  5. 5.Nencki Institute of Experimental BiologyWarsawPoland

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